천연화합물과 그 합성 유도체에 의한 화학발암과 돌연변이 억제

Abstract

Abstract Chemoprevention has been shown to be an extremly promising approach to the prevention of invasive cancer. Through the identification of chemopreventive agents that block or reverse the process of carcinogenesis, new strategies of early intervention can be developed for patients at high risk that potentially prevent the onset of invasive and metastatic phases of cancer. This articles reviews the our result in chemoprevention research, including natural products such as capsaicin, dially sulfide and gingerol, and structurally related compounds such as chlorophyllin, dehydroparadol and 2-(allythio)pyrazine.