개흉술후 Morphine을 이용한 흉부와 요부 경막외 자가통증조절간에는 차이가 없다

Abstract

BACKGROUND With different injection levels, the dose-requirements of epidural opioids association with lipid solubility are controversial. The purpose of this study was to compare the effect of patient controlled lumbar(L group) and thoracic(T group) epidural morphine on dose-requirements, analgesia and side effects after thoracotomy. METHODS Twenty patients were randomly assigned into one of two groups. Before the induction of general anesthesia, the epidural taps with 17G with Tuohy needle were done on the 6th or 7th thoracic and 2nd or 3rd lumbar intervertebral levels, respectively. The epidural catheter tips were placed 3~4 cm above the needle tips in either groups . Morphine 3 mg in 3 ml normal saline was administered via the epidural catheter in all the patients immediately at the end of surgical manipulation. PCA/basal infusion dose and lockout interval was 0.02 mg/once, 0.08 mg/hr and 5min respectively. After the initial dose dose-requirements were checked at 4, 8, 24 and 48hour and pain was assessed on visual analogue scale at 1, 4, 8, 24 and 48hour. Side effects were observed. RESULTS: There were no significant difference between groups in the dose-requirements of morphine, their analgesia and side effects. CONCLUSIONS Lumbar epidural morphine provides postoperative analgesia after thoracotomy that is clinically indistinguishable from that provided by thoracic epidural morphine with respect to dosage, quality of analgesia and side effect.