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Treponema pallidum 특이항체 검출을 위한 효소면역법 Trepanostika TM 의 임상적 유용

Other Titles
 Clinical Usefulness of TrepanostikaTM, Enzyme-Linked Immunosorbent Assay for Detection of Treponema pallidum-Specific Antibody 
 김영아  ;  조동희  ;  김현숙 
 Korean Journal of Clinical Pathology (대한임상병리학회지), Vol.18(2) : 255-258, 1998 
Journal Title
 Korean Journal of Clinical Pathology (대한임상병리학회지) 
Issue Date
Background :The TrepanostikaTM is an enzyme-linked immunosorbent assay (ELISA) for the qualitative determination of specific antibody (Ab) to Treponema pallidum. It is important to detect Treponenia pallidum-specific Ab to confirm syphilis in patients with positive nontreponemal result or at late latent stage/late stage. Currently various ELISA methods for Treponema pallidum-specific Ab haute been developed in addition to widely used treponemal tests such as fluorescent treponemal antibody absorption (FTA-ABS) test or Treponema pallidum hemagglutination (TPHA) test. We evaluated TrepanostikaTM, anti-treponemal ELISA test. Method :The sensitivity anti specificity of this ELISA method for detecting Treponema pallidum-specific Ab (TrepanostikaTM) were evaluated and compared with other treponemal tests such as FTA-ABS and TPHA. Result :The sensitivity and specificity of TrepanostikaTM were 55.7% and 95.8%, respectively. The concordance rate with FTA-ABS was 98.9% (283/286) and 100% (272/272) with TPHA. Conclusion :TrepanostikaTM which has similar sensitivity and specificity with FTA-ABS or TPHA could replace the well-known treponemal test such as FTA-ABS or TPHA.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hyon Suk(김현숙) ORCID logo https://orcid.org/0000-0001-5662-7740
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