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기능성 소화불량증과 역류성 식도염에서 위배출능 및 위 내 분포의 평가

Other Titles
 Evaluation of Gastric Emptying and Intragastric Destribution in Functional Dyspepsia and Reflux Esophagitis 
Authors
 김태일  ;  박인서  ;  전재윤  ;  이관식  ;  박효진  ;  이종두  ;  정준표 
Citation
 Korean Journal of Gastroenterology (대한소화기학회지), Vol.31(4) : 411-420, 1998 
Journal Title
 Korean Journal of Gastroenterology (대한소화기학회지) 
ISSN
 1598-9992 
Issue Date
1998
Abstract
Background/Aims: Delayed gastric emptying and postprandial antral hypomotility are observed in patients with functional dyspepsia. These gastric motility abnormalities can be also associated with pathophysiology of reflux esophagitis. Thus, we studied intragastric food distribution and gastric emptying to examine food maldistribution in functional dyspepsia and reflux esophagitis. Methods: The patients with functional dyspepsia were categorized by prevalent discomfort patients (Group I, 10) and prevalent pain patients (Group II, 12). These two groups of patients ingested test meal labelled with technetium-99m. Patients with reflux esophagitis (Group IIl, 11) and healthy volunteers (Control, 2) ingested the same meal. Serial images of the gastric area were taken for 90 minutes and parameters of gastric emptying and intragastric distribution were examined for the regions of proximal, distal and total stomach. Results: Parameters of total gastric emptying (T1/2, retention at 30 min and 90 min, total gastric residence) in patients with functional dyspepsia and reflux esophagitis were not significantly different from those of controls. In the group II, all parameters of intragastric distribution were not different from those of controls. However, in the group I, initial activity (75.0%) in proximal gastric area after ingestion was significantly lower than that in controls (86.7%). Food distribution [maximal distal content (41.1%), distal gastric residence (41.1%)] in distal gastric area was significantly higher than that in controls [maximal distal content (28.5%), distal gastric residence (28.8%)]. In the Group III parameters of intragastric distribution are similar to those of the group I . Conclusions: Prevalent discomfort group of functional dyspepsia showed abnormal intragastric distribution of ingested food. On the other hand, they did not show delayed gastric emptying. The group of reflux esophagitis showed similar results.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Hyo Jin(박효진) ORCID logo https://orcid.org/0000-0003-4814-8330
Lee, Kwan Sik(이관식) ORCID logo https://orcid.org/0000-0002-3672-1198
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/176456
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