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Predictors of Good Outcomes in Patients With Failed Endovascular Thrombectomy

DC FieldValueLanguage
dc.contributor.author김동준-
dc.contributor.author김병문-
dc.contributor.author김영대-
dc.contributor.author김준휘-
dc.contributor.author남효석-
dc.contributor.author허지회-
dc.date.accessioned2020-06-17T00:55:03Z-
dc.date.available2020-06-17T00:55:03Z-
dc.date.issued2020-05-
dc.identifier.issn1229-6929-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/176180-
dc.description.abstractObjective: Endovascular thrombectomy (EVT) fails in approximately 20% of anterior circulation large vessel occlusion (AC-LVO). Nonetheless, the factors that affect clinical outcomes of non-recanalized AC-LVO despite EVT are less studied. The purpose of this study was to identify the factors affecting clinical outcomes in non-recanalized AC-LVO patients despite EVT. Materials and methods: This was a retrospective analysis of clinical and imaging data from 136 consecutive patients who demonstrated recanalization failure (modified thrombolysis in cerebral ischemia [mTICI], 0-2a) despite EVT for AC-LVO. Data were collected in prospectively maintained registries at 16 stroke centers. Collateral status was categorized into good or poor based on the CT angiogram, and the mTICI was categorized as 0-1 or 2a on the final angiogram. Patients with good (modified Rankin Scale [mRS], 0-2) and poor outcomes (mRS, 3-6) were compared in multivariate analysis to evaluate the factors associated with a good outcome. Results: Thirty-five patients (25.7%) had good outcomes. The good outcome group was younger (odds ratio [OR], 0.962; 95% confidence interval [CI], 0.932-0.992; p = 0.015), had a lower incidence of hypertension (OR, 0.380; 95% CI, 0.173-0.839; p = 0.017) and distal internal carotid artery involvement (OR, 0.149; 95% CI, 0.043-0.520; p = 0.003), lower initial National Institute of Health Stroke Scale (NIHSS) (OR, 0.789; 95% CI, 0.713-0.873; p < 0.001) and good collateral status (OR, 13.818; 95% CI, 3.971-48.090; p < 0.001). In multivariate analysis, the initial NIHSS (OR, 0.760; 95% CI, 0.638-0.905; p = 0.002), good collateral status (OR, 14.130; 95% CI, 2.264-88.212; p = 0.005) and mTICI 2a recanalization (OR, 5.636; 95% CI, 1.216-26.119; p = 0.027) remained as independent factors with good outcome in non-recanalized patients. Conclusion: Baseline NIHSS score, good collateral status, and mTICI 2a recanalization remained independently associated with clinical outcome in non-recanalized patients. mTICI 2a recanalization would benefit patients with good collaterals in non-recanalized AC-LVO patients despite EVT.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Society of Radiology-
dc.relation.isPartOfKOREAN JOURNAL OF RADIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titlePredictors of Good Outcomes in Patients With Failed Endovascular Thrombectomy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorHyungjong Park-
dc.contributor.googleauthorByung Moon Kim-
dc.contributor.googleauthorJang Hyun Baek-
dc.contributor.googleauthorJun Hwee Kim-
dc.contributor.googleauthorJi Hoe Heo-
dc.contributor.googleauthorDong Joon Kim-
dc.contributor.googleauthorHyo Suk Nam-
dc.contributor.googleauthorYoung Dae Kim-
dc.identifier.doi10.3348/kjr.2019.0578-
dc.contributor.localIdA00410-
dc.contributor.localIdA00498-
dc.contributor.localIdA00498-
dc.contributor.localIdA00702-
dc.contributor.localIdA00702-
dc.contributor.localIdA05754-
dc.contributor.localIdA05754-
dc.contributor.localIdA01273-
dc.contributor.localIdA01273-
dc.contributor.localIdA04369-
dc.contributor.localIdA04369-
dc.relation.journalcodeJ02884-
dc.identifier.eissn2005-8330-
dc.identifier.pmid32323503-
dc.subject.keywordCerebral infarction-
dc.subject.keywordPredictive factor-
dc.subject.keywordPrognosis-
dc.subject.keywordThrombectomy-
dc.contributor.alternativeNameKim, Dong Joon-
dc.contributor.affiliatedAuthor김동준-
dc.contributor.affiliatedAuthor김병문-
dc.contributor.affiliatedAuthor김병문-
dc.contributor.affiliatedAuthor김영대-
dc.contributor.affiliatedAuthor김영대-
dc.contributor.affiliatedAuthor김준휘-
dc.contributor.affiliatedAuthor김준휘-
dc.contributor.affiliatedAuthor남효석-
dc.contributor.affiliatedAuthor남효석-
dc.contributor.affiliatedAuthor허지회-
dc.contributor.affiliatedAuthor허지회-
dc.citation.volume21-
dc.citation.number5-
dc.citation.startPage582-
dc.citation.endPage587-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF RADIOLOGY, Vol.21(5) : 582-587, 2020-05-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers

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