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Comparison of Half-Time and Half-Irradiance Photodynamic Therapy in Nonresolving Central Serous Chorioretinopathy

Authors
 Ji Hwan Lee  ;  Sung Chul Lee  ;  Christopher Seungkyu Lee 
Citation
 JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, Vol.36(2) : 109-115, 2020-03 
Journal Title
 JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS 
ISSN
 1080-7683 
Issue Date
2020-03
Keywords
central serous chorioretinopathy ; choroid ; photochemotherapy
Abstract
Purpose: To compare the efficacy of half-time and half-irradiance photodynamic therapy (PDT) in patients with nonresolving central serous chorioretinopathy (CSC) Methods: This retrospective study included 32 patients with nonresolving CSC, of whom 14 were treated with half-time PDT and 18 with half-irradiance PDT. Therapeutic outcomes, including central retinal thickness (CRT), subretinal fluid (SRF) height, subfoveal choroidal thickness (SFCT), thickness of the Haller layer (HL), thickness of the choriocapillaris/Sattler layer (SL), and best-corrected visual acuity (BCVA), were measured at baseline, and at 1 and 3 months after treatment. Results: CRT, SRF, and SFCT decreased significantly at 1 and 3 months after treatment in both groups. Thickness of the HL decreased significantly at 1 and 3 months, whereas thickness of the choriocapillaris/SL did not. BCVA demonstrated a significant improvement at 3 months in both groups. Changes in outcome parameters were not significantly different between the 2 groups. Conclusion: Both half-time and half-irradiance PDT were effective in SRF resolution and visual improvement, reducing choroidal thickness mainly on HL.
Full Text
https://www.liebertpub.com/doi/abs/10.1089/jop.2019.0003
DOI
10.1089/jop.2019.0003
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Christopher Seungkyu(이승규) ORCID logo https://orcid.org/0000-0001-5054-9470
Lee, Ji Hwan(이지환) ORCID logo https://orcid.org/0000-0003-1759-8195
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/176006
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