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Postcontrast Acute Kidney Injury After Computed Tomography Pulmonary Angiography for Acute Pulmonary Embolism

Authors
 Ara Cho  ;  Min Joung Kim  ;  Je Sung You  ;  Hye Jung Shin  ;  Eun Ju Lee  ;  Incheol Park  ;  Sung Phil Chung  ;  Ji Hoon Kim 
Citation
 JOURNAL OF EMERGENCY MEDICINE, Vol.57(6) : 798-804, 2019-12 
Journal Title
 JOURNAL OF EMERGENCY MEDICINE 
ISSN
 0736-4679 
Issue Date
2019-12
Keywords
acute kidney injury ; acute pulmonary embolism ; computed tomography pulmonary angiography ; postcontrast acute kidney injury ; renal function
Abstract
Background: Despite the widespread use of computed tomography pulmonary angiography with contrast media for the diagnosis of acute pulmonary embolism, high-quality evidence on risk factors for postcontrast acute kidney injury related to its use is lacking. Objective: The present study aimed to investigate whether the level of estimated glomerular filtration rate observed in the emergency department (ED) is significantly associated with the occurrence of postcontrast acute kidney injury in patients undergoing computed tomography pulmonary angiography. Methods: We performed a retrospective observational study using data automatically collected by a clinical data retrieval system from 1300 patients who underwent computed tomography pulmonary angiography for suspected acute pulmonary embolism in the ED. A total of 632 patients were selected for the study after exclusion. Univariate analyses were performed to identify significant risk factors for postcontrast acute kidney injury (the primary outcome). Multivariate logistic regression analysis was used to confirm the effect of estimated glomerular filtration rate in the ED on the occurrence of postcontrast acute kidney injury after adjustment for confounding variables. Results: The total incidence rate of postcontrast acute kidney injury was 6.49% (41/632 patients). No statistically significant association between estimated glomerular filtration rate and the risk of postcontrast acute kidney injury was observed. Conclusion: Our study findings could serve as useful reference for physicians who are concerned about performing computed tomography pulmonary angiography for fear of renal function deterioration.
Full Text
https://www.sciencedirect.com/science/article/pii/S0736467919307796
DOI
10.1016/j.jemermed.2019.09.006
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Min Joung(김민정) ORCID logo https://orcid.org/0000-0003-1634-5209
Kim, Ji Hoon(김지훈) ORCID logo https://orcid.org/0000-0002-0070-9568
Park, In Cheol(박인철) ORCID logo https://orcid.org/0000-0001-7033-766X
You, Je Sung(유제성) ORCID logo https://orcid.org/0000-0002-2074-6745
Chung, Sung Phil(정성필) ORCID logo https://orcid.org/0000-0002-3074-011X
Cho, Ara(조아라)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/175845
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