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외상성 뇌손상 후 발생한 구강 안면 운동이상에서 −메토클로프라마이드의 투여 후 호전 1예 : 증례 보고

Other Titles
 Trial of Metoclopramide on Oro-facial Dyskinesia Following Traumatic Brain Injury: A Case Report 
Authors
 김승기  ;  김준엽 
Citation
 Brain & Neurorehabilitation, Vol.7(2) : 147-150, 2014 
Journal Title
 Brain & Neurorehabilitation 
ISSN
 1976-8753 
Issue Date
2014
Keywords
dopamine receptors ; dyskinesias ; metoclopramide
Abstract
Oro-facial dyskinesia is characterized by involuntary repetitive movements of the tongue, lip, or jaw, which is known to be derived by variable causes. Pre- and post-synaptic dopamine receptor abnormalities by degenerative changes in the brain seem to be the key pathophysiology, but the exact mechanism still remained to be unknown. Metoclopramide can pass the blood-brain barrier, which is known for a selective presynaptic autoregulating dopamine D2 receptor antagonist in the brain, and is usually prescribed for dyspepsia, nausea and vomiting. In particular, it was also reported to improve the symptoms of diurnal bruxism after brain injury. With reviewing some of literatures, we present a case of 27 year old man with traumatic brain injury who showed improvement of oro-facial dyskinesia after taking oral metoclopramide.
Files in This Item:
T999201401.pdf Download
DOI
10.12786/bn.2014.7.2.147
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seung Ki(김승기) ORCID logo https://orcid.org/0000-0002-8823-6258
Kim, Jun Yup(김준엽)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/175695
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