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Utility of FDG PET/CT for Preoperative Staging of Non-Small Cell Lung Cancers Manifesting as Subsolid Nodules With a Solid Portion of 3 cm or Smaller
DC Field | Value | Language |
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dc.contributor.author | 서영주 | - |
dc.date.accessioned | 2020-04-13T17:00:23Z | - |
dc.date.available | 2020-04-13T17:00:23Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 0361-803X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/175610 | - |
dc.description.abstract | OBJECTIVE. The objective of our study was to investigate the utility of FDG PET/CT for the preoperative staging of subsolid non-small cell lung cancers (NSCLCs) with a solid portion size of 3 cm or smaller. MATERIALS AND METHODS. We retrospectively enrolled 855 patients with pathologically proven NSCLCs manifesting as subsolid nodules with a solid portion of 3 cm or smaller on CT. We then compared the diagnostic performances of FDG PET/CT and chest CT for detecting lymph node (LN), intrathoracic, or distant metastases in patients who underwent preoperative chest CT and FDG PET/CT. After propensity score matching, we compared the diagnostic performance of FDG PET/CT in the group who underwent both chest CT and FDG PET/CT with that of chest CT in patients who did not undergo FDG PET/CT. RESULTS. There were LN metastases in 25 of 765 patients (3.3%) who underwent surgical LN dissection or biopsy and intrathoracic or distant metastasis in two of 855 patients (0.2%). For LN staging, FDG PET/CT showed a sensitivity of 44.0%, specificity of 81.5%, positive predictive value of 9.6%, negative predictive value of 97.0%, and accuracy of 79.9%, which were lower than those of chest CT for accuracy (p < 0.0001). FDG PET/CT could not accurately detect any intrathoracic or distant metastasis. After propensity score matching, the diagnostic accuracy for LN staging of FDG PET/CT in the group who underwent both CT and FDG PET/CT was lower than that of chest CT in the group who did not undergo FDG PET/CT (p = 0.002), and the diagnostic accuracy for intrathoracic and distant metastases was not different (p > 0.999). CONCLUSION. FDG PET/CT has limited utility in preoperatively detecting LN or distant metastasis in patients with subsolid NSCLCs with a solid portion size of 3 cm or smaller. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springfield, Ill., Thomas | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF ROENTGENOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Utility of FDG PET/CT for Preoperative Staging of Non-Small Cell Lung Cancers Manifesting as Subsolid Nodules With a Solid Portion of 3 cm or Smaller | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Young Joo Suh | - |
dc.contributor.googleauthor | Chang Min Park | - |
dc.contributor.googleauthor | Kyunghwa Han | - |
dc.contributor.googleauthor | Sun Kyung Jeon | - |
dc.contributor.googleauthor | Hyungjin Kim | - |
dc.contributor.googleauthor | Eui Jin Hwang | - |
dc.contributor.googleauthor | Jong Hyuk Lee | - |
dc.contributor.googleauthor | Jin Chul Paeng | - |
dc.contributor.googleauthor | Chang Hoon Lee | - |
dc.contributor.googleauthor | Young Tae Kim | - |
dc.contributor.googleauthor | Jin Mo Goo | - |
dc.identifier.doi | 10.2214/AJR.19.21811 | - |
dc.contributor.localId | A01892 | - |
dc.relation.journalcode | J00116 | - |
dc.identifier.eissn | 1546-3141 | - |
dc.identifier.pmid | 31846374 | - |
dc.identifier.url | https://www.ajronline.org/doi/full/10.2214/AJR.19.21811 | - |
dc.subject.keyword | CT | - |
dc.subject.keyword | PET | - |
dc.subject.keyword | cancer staging | - |
dc.subject.keyword | non–small cell lung cancer | - |
dc.subject.keyword | subsolid nodule | - |
dc.contributor.alternativeName | Suh, Young Joo | - |
dc.contributor.affiliatedAuthor | 서영주 | - |
dc.citation.volume | 214 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 514 | - |
dc.citation.endPage | 523 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF ROENTGENOLOGY, Vol.214(3) : 514-523, 2020 | - |
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