Cited 39 times in
Pathophysiologic and Therapeutic Perspectives Based on Thrombus Histology in Stroke
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김동준 | - |
dc.contributor.author | 김병문 | - |
dc.contributor.author | 김영대 | - |
dc.contributor.author | 남효석 | - |
dc.contributor.author | 허지회 | - |
dc.date.accessioned | 2020-04-13T16:47:20Z | - |
dc.date.available | 2020-04-13T16:47:20Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 2287-6391 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/175512 | - |
dc.description.abstract | Recent advances in endovascular thrombectomy have enabled the histopathologic analysis of fresh thrombi in patients with acute stroke. Histologic analysis has shown that the thrombus composition is very heterogeneous between patients. However, the distribution pattern of each thrombus component often differs between patients with cardiac thrombi and those with arterial thrombi, and the efficacy of endovascular thrombectomy is different according to the thrombus composition. Furthermore, the thrombus age is related to the efficacy of reperfusion therapy. Recent studies have shown that neutrophils and neutrophil extracellular traps contribute to thrombus formation and resistance to reperfusion therapy. Histologic features of thrombi in patients with stroke may provide some clues to stroke etiology, which is helpful for determining the strategy of stroke prevention. Research on thrombus may also be helpful for improving reperfusion therapy, including the development of new thrombolytic agents. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Stroke Society | - |
dc.relation.isPartOf | JOURNAL OF STROKE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Pathophysiologic and Therapeutic Perspectives Based on Thrombus Histology in Stroke | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Ji Hoe Heo | - |
dc.contributor.googleauthor | Hyo Suk Nam | - |
dc.contributor.googleauthor | Young Dae Kima | - |
dc.contributor.googleauthor | Jin Kyo Choi | - |
dc.contributor.googleauthor | Byung Moon Kim | - |
dc.contributor.googleauthor | Dong Joon Kim | - |
dc.contributor.googleauthor | Il Kwon | - |
dc.identifier.doi | 10.5853/jos.2019.03440 | - |
dc.contributor.localId | A00410 | - |
dc.contributor.localId | A00498 | - |
dc.contributor.localId | A00702 | - |
dc.contributor.localId | A01273 | - |
dc.contributor.localId | A04369 | - |
dc.relation.journalcode | J01758 | - |
dc.identifier.eissn | 2287-6405 | - |
dc.identifier.pmid | 32027792 | - |
dc.contributor.alternativeName | Kim, Dong Joon | - |
dc.contributor.affiliatedAuthor | 김동준 | - |
dc.contributor.affiliatedAuthor | 김병문 | - |
dc.contributor.affiliatedAuthor | 김영대 | - |
dc.contributor.affiliatedAuthor | 남효석 | - |
dc.contributor.affiliatedAuthor | 허지회 | - |
dc.citation.volume | 22 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 64 | - |
dc.citation.endPage | 75 | - |
dc.identifier.bibliographicCitation | JOURNAL OF STROKE, Vol.22(1) : 64-75, 2020 | - |
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