0 99

Cited 0 times in

Histologic analysis following grafting of damaged extraction sockets using deproteinized bovine or porcine bone mineral: A randomized clinical trial

 Tae‐Hwan Koo  ;  Young Woo Song  ;  Jae‐Kook Cha  ;  Ui‐Won Jung  ;  Chang‐Sung Kim  ;  Jung‐Seok Lee 
 CLINICAL ORAL IMPLANTS RESEARCH, Vol.31(1) : 93-102, 2020 
Journal Title
Issue Date
Animals ; Bone Substitutes* ; Cattle ; Collagen ; Humans ; Minerals ; Swine ; Tooth Extraction ; Tooth Socket*
bone regeneration ; bone substitutes ; clinical research ; clinical trials ; guided tissue regeneration
OBJECTIVES: This study histologically analyzed biopsy samples obtained from sites of damaged extraction socket grafting using deproteinized bovine bone mineral (DBBM) or deproteinized porcine bone mineral (DPBM) with coverage by a collagen membrane. MATERIAL AND METHODS: One hundred patients participated in this randomized controlled clinical trial of extraction socket grafts performed in cases of periodontally compromised teeth. All participants were blinded to their group allocations, and each material was grafted with coverage by collagen membranes after extraction of the tooth and removal of granulation tissue. At implant placement at 4 months, a biopsy was harvested at the implant site using a trephine was analyzed histologically. RESULTS: Eighty-five biopsy samples were acquired, of which 81 were finally included in the histologic analysis (42 in DBBM and 39 in DPBM group). Both DBBM and DPBM groups showed comparable proportions of residual biomaterial (12.37 ± 5.67% and 12.21 ± 5.75%, respectively), newly formed bone (15.07 ± 10.52% and 18.47 ± 11.47%, respectively), and nonmineralized tissue (72.56 ± 10.07% and 71.55 ± 15.47%, respectively). There were no significant differences in these histologic parameters between the two groups with different biomaterials. CONCLUSION: Comparable histologic bone formation was found in both socket grafted groups with DBBM or DPBM covered by collagen membranes in periodontally damaged extraction sockets. However, a wide variation in new bone formation was found after 4 months of postsurgical healing and a tendency of higher new bone formation was shown at damaged sockets that had an intact unilateral residual wall regardless of buccal or lingual side.
Full Text
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chang Sung(김창성) ORCID logo https://orcid.org/0000-0003-3902-1071
Song, Young Woo(송영우) ORCID logo https://orcid.org/0000-0003-1835-5646
Lee, Jung Seok(이중석) ORCID logo https://orcid.org/0000-0003-1276-5978
Jung, Ui Won(정의원) ORCID logo https://orcid.org/0000-0001-6371-4172
Cha, Jae Kook(차재국) ORCID logo https://orcid.org/0000-0001-6817-9834
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.