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Macular Choroidal Thickness Changes in Development, Progression, and Spontaneous Resolution of Epiretinal Membrane

Authors
 Eun Young Choi  ;  Jongwook Han  ;  Sung Chul Lee  ;  Christopher Seungkyu Lee 
Citation
 OPHTHALMIC SURGERY LASERS & IMAGING RETINA, Vol.50(10) : 627-634, 2019 
Journal Title
 OPHTHALMIC SURGERY LASERS & IMAGING RETINA 
ISSN
 2325-8160 
Issue Date
2019
MeSH
Aged ; Choroid/pathology* ; Disease Progression ; Epiretinal Membrane/pathology* ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Tomography, Optical Coherence/methods
Abstract
BACKGROUND AND OBJECTIVE: To evaluate the association between macular choroidal thickness and the development, progression, and resolution of epiretinal membrane (ERM). PATIENTS AND METHODS: The patients (n = 38) with unilateral ERM eyes with definitive changes on optical coherence tomography (OCT) and healthy fellow eyes were observed retrospectively. ERM eyes were divided into three groups: Development/new-onset group (n = 14), progression group (n = 13), and resolution group (n = 11). In each group, the average changes of macular choroidal thickness over time in ERM eyes were compared with those in the fellow eyes RESULTS: Choroidal thickness significantly decreased from 174.0 μm at baseline to 132.3 μm at event time (P = .001) in the development group, and from 140.0 μm ± 30.0 μm to 120.5 μm (P = .002) in the progression group. Conversely, a significant increase in choroidal thickness was observed in the resolution group (from 205.2 μm to 222.6 μm; P = .004). The fellow eyes showed no significant changes in choroidal thickness in all three groups. CONCLUSION: Choroidal thinning in newly developed or significantly progressed ERM eyes and choroidal thickening in spontaneously resolved ERM eyes suggest a clinical implication of choroidal changes in ERM.
Full Text
https://www.healio.com/ophthalmology/journals/osli/2019-10-50-10/%7B1a8c244e-7a28-4278-92a8-d5bc2c49c1f2%7D/macular-choroidal-thickness-changes-in-development-progression-and-spontaneous-resolution-of-epiretinal-membrane
DOI
10.3928/23258160-20191009-05
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
Lee, Christopher Seungkyu(이승규) ORCID logo https://orcid.org/0000-0001-5054-9470
Choi, Eun Young(최은영) ORCID logo https://orcid.org/0000-0002-1668-6452
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/174784
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