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Feasibility of Spin-Echo Echo-Planar Imaging MR Elastography in Livers of Children and Young Adults Adults

DC FieldValueLanguage
dc.contributor.author고홍-
dc.contributor.author김명준-
dc.contributor.author김승-
dc.contributor.author신현주-
dc.contributor.author윤혜성-
dc.contributor.author이미정-
dc.contributor.author한경화-
dc.contributor.author한석주-
dc.date.accessioned2020-02-11T06:29:00Z-
dc.date.available2020-02-11T06:29:00Z-
dc.date.issued2019-
dc.identifier.issn2384-1095-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/174694-
dc.description.abstractPurpose: To assess the feasibility of the use of spin-echo echo-planar imaging (SE-EPI) magnetic resonance elastography (MRE) in livers of children and young adults. Materials and Methods: Patients (≤ 20 years old) who underwent 3T SE-EPI MRE were included retrospectively. Subjects were divided into three groups according to the purpose of the liver MRI: suspicion of fatty liver or focal fat deposition in the liver (FAT group), liver fibrosis after receiving a Kasai operation from biliary atresia (BA group), and hepatic iron deposition after receiving chemotherapy or transfusions (IRON group). Technical failure of MRE was defined when a stiffness map showed no pixel value with a confidence index higher than 95%, and the patients were divided as success and failure groups accordingly. Clinical findings including age, gender, weight, height, and body mass index and magnetic resonance imaging results including proton density fat fraction (PDFF), T2*, and MRE values were assessed. Factors affecting failure of MRE were evaluated and the image quality in wave propagation image and stiffness map was evaluated using the appropriate scores. Results: Among total 240 patients (median 15 years, 211 patients in the FAT, 21 patients in the BA, and 8 patients in the IRON groups), technical failure was noted in six patients in the IRON group (6/8 patients, 75%), while there were no failures noted in the FAT and BA groups. These six patients had T2* values ranging from 0.9 to 3.8 ms. The image quality scores were not significantly different between the FAT and BA groups (P > 0.999), while the scores were significantly lower in the IRON group (P < 0.001). Conclusion: The 3T SE-EPI MRE in children and young adults had a high technical success rate. The technical failure was occurred in children with decreased T2* value (≤ 3.8 ms) from iron deposition.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Society of Magnetic Resonance in Medicine-
dc.relation.isPartOfInvestigative Magnetic Resonance Imaging-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleFeasibility of Spin-Echo Echo-Planar Imaging MR Elastography in Livers of Children and Young Adults Adults-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아청소년과학교실)-
dc.contributor.googleauthorJin Kyem Kim-
dc.contributor.googleauthorHaesung Yoon-
dc.contributor.googleauthorMi-Jung Lee-
dc.contributor.googleauthorMyung-Joon Kim-
dc.contributor.googleauthorKyunghwa Han-
dc.contributor.googleauthorHong Koh-
dc.contributor.googleauthorSeung Kim-
dc.contributor.googleauthorSeok Joo Han-
dc.contributor.googleauthorHyun Joo Shin-
dc.identifier.doi10.13104/imri.2019.23.3.251-
dc.contributor.localIdA00156-
dc.contributor.localIdA00425-
dc.contributor.localIdA00425-
dc.contributor.localIdA00651-
dc.contributor.localIdA00651-
dc.contributor.localIdA02178-
dc.contributor.localIdA02178-
dc.contributor.localIdA04989-
dc.contributor.localIdA04989-
dc.contributor.localIdA02774-
dc.contributor.localIdA02774-
dc.contributor.localIdA04267-
dc.contributor.localIdA04267-
dc.contributor.localIdA04288-
dc.contributor.localIdA04288-
dc.relation.journalcodeJ01186-
dc.identifier.eissn2384-1109-
dc.subject.keywordChild-
dc.subject.keywordYoung adult-
dc.subject.keywordLiver-
dc.subject.keywordMagnetic resonance imaging-
dc.subject.keywordElasticity imaging techniques-
dc.contributor.alternativeNameKoh, Hong-
dc.contributor.affiliatedAuthor고홍-
dc.contributor.affiliatedAuthor김명준-
dc.contributor.affiliatedAuthor김명준-
dc.contributor.affiliatedAuthor김승-
dc.contributor.affiliatedAuthor김승-
dc.contributor.affiliatedAuthor신현주-
dc.contributor.affiliatedAuthor신현주-
dc.contributor.affiliatedAuthor윤혜성-
dc.contributor.affiliatedAuthor윤혜성-
dc.contributor.affiliatedAuthor이미정-
dc.contributor.affiliatedAuthor이미정-
dc.contributor.affiliatedAuthor한경화-
dc.contributor.affiliatedAuthor한경화-
dc.contributor.affiliatedAuthor한석주-
dc.contributor.affiliatedAuthor한석주-
dc.citation.volume23-
dc.citation.number3-
dc.citation.startPage251-
dc.citation.endPage258-
dc.identifier.bibliographicCitationInvestigative Magnetic Resonance Imaging, Vol.23(3) : 251-258, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Others (기타) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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