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Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli

Authors
 Kwangjin Ahn  ;  Gyu Yel Hwang  ;  Young Keun Kim  ;  Hyo Youl Kim  ;  Hye Ran Jeong  ;  Jun Sung Hong  ;  Young Uh 
Citation
 INFECTION AND CHEMOTHERAPY, Vol.51(2) : 177-182, 2019 
Journal Title
 INFECTION AND CHEMOTHERAPY 
ISSN
 2093-2340 
Issue Date
2019
Keywords
Carbapenemase-producing Enterobacteriaceae ; Escherichia coli ; New Delhi metallo-enzyme carbapenemase ; Outbreak control ; Oxacillin-hydrolyzing beta-lactamase
Abstract
Carbapenemase-producing Enterobacteriaceae (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or infected with carbapenem-resistant Escherichia coli strains. All of E. coli isolates co-produced blaNDM-5 and blaOXA-181 carbapenemase genes and shared ≥88% clonal relatedness on the basis of a cladistic calculation of the distribution of pulsed-field gel electrophoresis patterns. Rapid detection of CPE is one of the most important factors to prevent CPE dissemination because it takes long time for CPE to become negative.
Files in This Item:
T201902606.pdf Download
DOI
10.3947/ic.2019.51.2.177
Appears in Collections:
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
Yonsei Authors
Hong, Jun Sung(홍준성)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/174473
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