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뇌성마비와 발달지연 환아에서 경련성 질환이 발달장애에 미치는 영향

Other Titles
 Effect of Seizure Disorders on Developmental Disability in Patients with Cerebral Palsy or Delayed Development 
 박은숙  ;  박창일  ;  신지철  ;  방인걸 
 Journal of the Korean Academy of Rehabilitation Medicine (대한재활의학회지), Vol.23(3) : 516-523, 1999 
Journal Title
 Journal of the Korean Academy of Rehabilitation Medicine (대한재활의학회지) 
Issue Date
Epilepsy ; Neonatal seizure ; Cerebral palsy ; Delayed development ; Bayley Scale Infant Development
Objective : To investigate the effect of epilepsy and neonatal seizure on development in children with cerebral palsy (CP) or delayed development (DD). Method : The subjects were 135 patients with CP or DD. Development was evaluated by Bayley Scale of Infant Development II (BSID II). Epilepsy was diagnosed on the base of clinical features, past history and electroencephalography. Results : The incidence of epilepsy was 18.4% in CP, and 37.8% in DD. Spastic quadriplegia of CP has the highest incidence of epilepsy (38.4%). First seizure attack was occurred before 6 months old of age in 66.7% of CP with epilepsy and in 64.3% of DD with epilepsy. The prevailing type of epilepsy was generalized seizure in DD (57.1%), partial seizure in CP (50.0%). The group with epilepsy had lower psychomotor and mental development quotient on BSID II than the group without epilesy (p<0.05). Polytherapy was more used to control epilepsy than monotherapy. Valproate (50.0%), phenobarbital (37.5%), carbamazepine (31.3%) were commonly used drugs for controlling epilepsy. Conclusion : The epilpesy has a negative effect on psychomotor and mental development in the children with CP or DD.
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1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
Yonsei Authors
Park, Eun Sook(박은숙) ORCID logo https://orcid.org/0000-0002-9144-3063
Park, Chang Il(박창일)
Shin, Ji Cheol(신지철) ORCID logo https://orcid.org/0000-0002-1133-1361
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