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정상인에서 단기간 사용한 Azopt의 효과

Other Titles
 The Effect of Short Term Use of Azopt in Normal Koreans 
Authors
 류창훈  ;  성공제 
Citation
 Journal of the Korean Ophthalmological Society (대한안과학회지), Vol.40(7) : 1960-1964, 1999 
Journal Title
JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY(대한안과학회지)
ISSN
 0378-6471 
Issue Date
1999
Keywords
Ahmed glaucoma valve implant ; Neovascular glaucoma ; Brinzolamide ; Carbonic anhydrase inhibitor ; Intraocular pressure
Abstract
Azopt(brinzolamide ophthalmic suspension,1%)is a carbonic anhydrase type II inhibitor,which reduces intraocular pressure by suppression of aque-ous humor production in ciliary process.It was developed as an agent which has little systemic side effect and was adjusted to physiologic ophthalmic environment. We observed the effect of intraocular pressure,pulsatile ocular blood flow and side effect to investigate the clinical effectiveness of Azopt in normal Azopt was instilled to 10 eyes of 10 volunteers and artificial tear was instilled to the other 10 eyes of 10 volunteers three times daily,respectively. We measured intraocular pressure by Goldman applanation tonometer at two hours,8 hours,1 day and 7 days after instillation.Pulsatile ocular blood flow,pupil diameter,blood pressure and pulse rate were also measured. Decrease of intraocular pressure after instillation of Azopt was statistically significant (p<0.05),compared with the pressure before instillation of Azopt and the decrease of pressure after instillation of artifical tear.No systemic side effect and ophthalmic discomfort was noted except for temporary visual blurring. Therefore we expect that Azopt will have a great effect on glaucoma patients in Korea who must be treated for long duration.
Files in This Item:
T199901634.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Seong, Gong Je(성공제) ORCID logo https://orcid.org/0000-0002-5456-4296
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/174032
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