0 25

Cited 0 times in

Use of the Endometriosis Fertility Index to Predict Natural Pregnancy after Endometriosis Surgery: A Single-Center Study

Authors
 Kim J.S.  ;  Lee C.W.  ;  Yun J.  ;  Lee J.H.  ;  Yun B.H.  ;  Park J.H.  ;  Seo S.K.  ;  Cho S.  ;  Choi Y.S.  ;  Lee B.S. 
Citation
 GYNECOLOGIC AND OBSTETRIC INVESTIGATION, Vol.84(1) : 86-93, 2019 
Journal Title
 GYNECOLOGIC AND OBSTETRIC INVESTIGATION 
ISSN
 0378-7346 
Issue Date
2019
MeSH
Adult ; Body Mass Index ; CA-125 Antigen/blood ; Endometriosis/complications ; Endometriosis/surgery* ; Female ; Fertility* ; Humans ; Infertility, Female/etiology ; Infertility, Female/surgery* ; Kaplan-Meier Estimate ; Postoperative Period ; Pregnancy ; Pregnancy Outcome ; Pregnancy Rate* ; ROC Curve ; Retrospective Studies
Keywords
Cumulative pregnancy rate ; Endometriosis ; Endometriosis fertility index ; Fertility
Abstract
AIMS: Our objective was to predict natural pregnancy after endometriosis surgery using the endometriosis fertility index (EFI). METHODS: A retrospective medical records review was conducted, examining patients surgically treated for endometriosis at a single center in Korea between January 2009 and February 2015. In total, 68 women attempting natural conception were analyzed by assessing age, preoperative serum CA-125, body mass index, revised American Fertility Society (rAFS) stage, EFI, and pregnancy outcome. Kaplan-Meier estimates and log-rank tests were used to generate cumulative natural pregnancy rate curves based on an EFI cut-point. A receiver-operating characteristic (ROC) curve was plotted for EFI. RESULTS: Seventy-seven patients attempted conceptions, resulting in 33 natural and 9 assisted conceptions. Excluding assisted conceptions, the mean EFI scores of 68 women who were not pregnant and pregnant were 5.43 ± 0.36 and 6.88 ± 0.28 respectively. The relation between EFI and natural pregnancy was significant (cumulative overall pregnancy rate, p = 0.006), whereas rAFS stage was not (univariate logistics, p = 0.853). The cut-point for maximum natural pregnancy outcomes was 6 (area under ROC curve = 0.710, 95% CI 0.586-0.835). CONCLUSION: The EFI is a reliable staging system for predicting natural pregnancy after endometriosis surgery. EFI scores can be used to guide postoperative treatment of women with endometriosis.
Full Text
https://www.karger.com/Article/Abstract/493264
DOI
10.1159/000493264
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jeong Sook(김정숙)
Park, Joo Hyun(박주현)
Seo, Seok Kyo(서석교) ORCID logo https://orcid.org/0000-0003-3404-0484
Yun, Bo Hyon(윤보현) ORCID logo https://orcid.org/0000-0001-5703-797X
Yun, Jisun(윤지선)
Lee, Byung Seok(이병석) ORCID logo https://orcid.org/0000-0001-6001-2079
Lee, Jae Hoon(이재훈) ORCID logo https://orcid.org/0000-0003-4223-1395
Cho, Si Hyun(조시현) ORCID logo https://orcid.org/0000-0003-2718-6645
Choi, Young Sik(최영식) ORCID logo https://orcid.org/0000-0002-1157-4822
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/173468
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse