0 286

Cited 0 times in

Amylase level in cervical drain fluid and anastomotic leakage after cervical oesophagogastrostomy

Authors
 Woo Sik Yu  ;  Joonho Jung  ;  Hyejung Shin  ;  Yunho Roh  ;  Go Eun Byun  ;  Dae Joon Kim  ;  Seokjin Haam  ;  Seong Yong Park 
Citation
 EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol.56(2) : 301-306, 2019 
Journal Title
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
ISSN
 1010-7940 
Issue Date
2019
Abstract
OBJECTIVES: Anastomotic leakage after oesophageal cancer surgery is a serious complication. The purpose of this study was to evaluate the possibility of anastomotic leakage by repeatedly measuring amylase levels in the fluid obtained from the drainage tube inserted at the cervical anastomotic site.

METHODS: Ninety-nine patients who underwent oesophagectomy and cervical oesophagogastrostomy between April 2014 and March 2017 were retrospectively reviewed. A drainage tube was placed at the anastomotic site, and amylase levels were measured daily from postoperative day (POD) 1 until oral feeding or confirmation of anastomotic leakage. The amylase levels were analysed with a linear mixed model.

RESULTS: The mean age of the patients was 64.9 ± 9.0 years, and there were 89 (89%) male patients. Almost all pathologies (92%) were squamous cell carcinomas. The anastomotic methods were as follows: 63 (63%) circular stapled, 33 (33%) hand-sewn and 3 (3%) semistapled. Anastomotic leakage was confirmed in 10 (10%) patients. The amylase levels increased until POD 2 in both the leakage and non-leakage groups, but the levels subsequently decreased in the non-leakage group, whereas the levels peaked on POD 3 in the leakage group. On performing the linear mixed model analysis, anastomotic leakage was significantly associated with the trends in postoperative amylase levels in the drainage tube (P < 0.001). Trends in the serum C-reactive protein levels and white blood cell count were not significantly associated with anastomotic leakage.

CONCLUSIONS: Amylase level trends measured in the cervical drain fluid can be a useful indicator of anastomotic leakage after cervical oesophagogastrostomy.
Full Text
https://academic.oup.com/ejcts/article/56/2/301/5305058
DOI
10 1093/ejcts/ezz008
Appears in Collections:
6. Others (기타) > Severance Hospital (세브란스병원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dae Joon(김대준)
Park, Seong Yong(박성용) ORCID logo https://orcid.org/0000-0002-5180-3853
Byun, Go Eun(변고은)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/173122
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links