90 211

Cited 0 times in

혈관 미주신경성 실신 환자에서 24시간 활동 심전도상 심박동수 변이의 분석

Other Titles
 Analysis of Heart Rate Variability in 24-Hour Holtor onitoring of Patients with Vasovagal Syncope 
 강태수  ;  김동주  ;  권혁문  ;  김인재  ;  변기현  ;  강석민  ;  홍범기  ;  김동수  ;  최의영  ;  이준희  ;  박운형  ;  김현승 
 Korean Circulation Journal (순환기), Vol.30(11) : 1417-1422, 2000 
Journal Title
Issue Date
Heart rate variability ; Frequency-domain analysis ; Time-domain analysis ; Vasovagal Syncope
Background and Objectives:Syncope is defined as a sudden temporary loss of consciousness associated with
a loss of postural tone with spontaneous recovery. It is a common clinical problem with complex and heterogeneous
etiologies, but vasovagal syncope is the main cause of unexplained syncope. Bradycardia and hypotension
by transient dysfunction of cardiac autonomic nervous system have been cited as the main pathophysiology of
the vasovagal syncope. Therefore, we studied whether analysis of heart rate variability (HRV) by 24-hour
ambulatory ECG monitoring would reflect autonomic imbalance between cardiac sympathetic and vagal
efferent activity in the patients of vasovagal syncope. Materials and Method:45 patients (male=22, female=
23, mean age=42.2±14 years) with syncope were enrolled, and divided into 2 subgroups according to the results
of head-up tilt test:head-up tilt test positive (group S1) and negative (group S0). A sex-matched control group
consisted of 9 healthy volunteers (male=3, female=6, mean age=41±6 years, Group C). The 24-hour ambulatory
ECG monitoring was performed in all groups, and R-R intervals were analyzed by time- and frequencydomain
methods. The time-domain measurements of HRV were mean NN (mean of all coupling intervals
between normal beat), ASDNN (mean of the standard deviations of all normal R-R intervals for 5-minute
segments of the entire recording), SDNN (standard deviation of all normal R-R intervals over 24 hours),
SDANN (standard deviation of average R-R intervals in all 5 minutes segments of the entire recording), rMSSD
(square root of the mean squared differences of successive R-R interval) and pNN50 (percent of differences
between adjacent normal R-R intervals more than 50ms during 24 hours), and frequency-domain measurements
were low frequency (LF), high frequency (HF) components and LF/HF ratio. Results:The LF/HF ratio was
significantly higher in syncope patients with positive results of head-up tilt test and syncope patients with
negative results than in control (p<0.05). The LF, HF, mean NN, ASDNN, SDNN, SDANN, rMSSD,
and pNN50 were not significantly different among these three groups.
Conclusion:These results suggest that
Files in This Item:
T200001483.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Seok Min(강석민) ORCID logo https://orcid.org/0000-0001-9856-9227
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.