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Wilm 종양의 예후인자와 술전 및 재발시 사용된 항암약물에 따른 생존율의 차이

Other Titles
 Prognostic Factor and Survival Rate of Preoperative and Recurred CasesChemotherapy in Wilms' Tumor 
Authors
 최영득  ;  한상원  ;  최승강  ;  고우진  ;  이중식  ;  이석영  ;  한석주  ;  황의호  ;  유철주  ;  김병수 
Citation
 Korean Journal of Urology (대한비뇨기과학회지), Vol.41(6) : 741-746, 2000 
Journal Title
 Korean Journal of Urology (대한비뇨기과학회지) 
ISSN
 0494-4747 
Issue Date
2000
Keywords
Wilms'tumor ; Chemotherapy ; Prognosis ; Survival
Abstract
Purpose: We evaluated the prognostic factors of Wilms` tumor and reviewed the survival rate by several chemotherapeutic drugs used in recurred group.Materials and Methods: We reviewed the records of 53 patients with Wilms` tumor that had been treated at the Yonsei University College of Medicine from Jan. 1970 to Jul. 1998. With regard to treatment, radical nephrectomy combined with radiotherapy and chemotherapy was performed according to protocol. In recurred group, we used cyclophosphamide, VP-16, cis-platinum, ifosfamide.Results: Following the NWTS-III, there were I 21, II 10, III 12, IV 7 and V 3 with stages. There were 43(81.1%) favorable and 10(18.9%) unfavorable type. Recurrence rates were I 14.2.%, II 40.0%, III 25.0%, IV 42.8%, V 33.3% with stages, favorable 11.6%, unfavorable 90% with histologic features. The survival rates for those with stage were I 100%, II 64.3%, III 91.7%, IV 80.0%, V 66.7%. The survival rates for those with favorable and unfavorable histologic features were 96.2% and 68.6%. There was no difference in survival and recurrence rate according to age, symptoms and preoperative chemotherapy. In recurred cases, no specific chemotherapeutic agent increased the survival rate of Wilms` tumor significantly. Conclusions: The stage and histopathologic finding were important in the prognosis of Wilms` tumor, and no specific chemotherapeutic agent showed to increase the survival rate significantly in recurred cases.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Choi, Young Deuk(최영득) ORCID logo https://orcid.org/0000-0002-8545-5797
Han, Sang Won(한상원) ORCID logo https://orcid.org/0000-0003-0941-1300
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/172112
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