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Composite neuroendocrine and adenocarcinoma of the common bile duct associated with Clonorchis sinensis: a case report
DC Field | Value | Language |
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dc.contributor.author | 김세훈 | - |
dc.contributor.author | 박영년 | - |
dc.contributor.author | 유정식 | - |
dc.contributor.author | 윤동섭 | - |
dc.date.accessioned | 2019-11-11T05:08:32Z | - |
dc.date.available | 2019-11-11T05:08:32Z | - |
dc.date.issued | 2000 | - |
dc.identifier.issn | 0172-6390 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/171645 | - |
dc.description.abstract | The biliary tract has neuroendocrine cells of endoderm origin similar to the gastrointestinal tract, however neuroendocrine tumors of the biliary tract are rare. We report a composite glandular-endocrine cell carcinoma of the common bile duct in a 64-year-old Korean man which was associated with Clonorchis sinensis. The patient complained of right upper quadrant abdominal pain. Several parasites of Clonorchis sinensis were removed during the percutaneous transbiliary drainage. Endoscopic retrograde cholangiopancreatography revealed a polypoid mass (3 x 3 cm) with central ulceration in the common bile duct. Pancreaticoduodenectomy was performed. Microscopic examination of the tumor revealed a composite small cell neuroendocrine carcinoma and adenocarcinoma. The small cell carcinoma component showed positive reaction to chromogranin A and neuron-specific enolase and it was located mainly in the deeper portion of the mass. The well-differentiated adenocarcinoma component showed a positive reaction to carcinoembryonic antigen and it was situated in the superficial portion of the mass. Exclusively, the small cell component metastasized to the lymph node. It is suggested that this tumor could arise from a multipotential stem cell and showed neuroendocrine and glandular differentiation and that Clonorchis sinensis could be a predisposing factor, as in cholangiocarcinoma. | - |
dc.description.statementOfResponsibility | prohibition | - |
dc.language | English | - |
dc.publisher | H.G.E. Update Medical Publishing | - |
dc.relation.isPartOf | Hepato-Gastroenterology | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adenocarcinoma/pathology* | - |
dc.subject.MESH | Adenocarcinoma/surgery | - |
dc.subject.MESH | Carcinoma, Small Cell/pathology* | - |
dc.subject.MESH | Carcinoma, Small Cell/surgery | - |
dc.subject.MESH | Cholangiopancreatography, Endoscopic Retrograde | - |
dc.subject.MESH | Clonorchiasis/pathology* | - |
dc.subject.MESH | Common Bile Duct Neoplasms/pathology* | - |
dc.subject.MESH | Common Bile Duct Neoplasms/surgery | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Tomography, X-Ray Computed | - |
dc.title | Composite neuroendocrine and adenocarcinoma of the common bile duct associated with Clonorchis sinensis: a case report | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학교실) | - |
dc.contributor.googleauthor | Se Hoon Kim | - |
dc.contributor.googleauthor | Hoon Kim | - |
dc.contributor.googleauthor | Young Nyun Park | - |
dc.contributor.googleauthor | Nyun Park | - |
dc.contributor.googleauthor | Dong Sup Yoon | - |
dc.contributor.googleauthor | Sup Yoon | - |
dc.contributor.googleauthor | Se Joon Lee | - |
dc.contributor.googleauthor | Joon Lee | - |
dc.contributor.googleauthor | Jeong Sik Yu | - |
dc.contributor.googleauthor | Sik Yu | - |
dc.contributor.googleauthor | Tae Woong Noh | - |
dc.contributor.googleauthor | Woong Noh | - |
dc.contributor.localId | A00610 | - |
dc.contributor.localId | A01563 | - |
dc.contributor.localId | A02500 | - |
dc.contributor.localId | A02548 | - |
dc.relation.journalcode | J00984 | - |
dc.identifier.pmid | 11020854 | - |
dc.contributor.alternativeName | Kim, Se Hoon | - |
dc.contributor.affiliatedAuthor | 김세훈 | - |
dc.contributor.affiliatedAuthor | 박영년 | - |
dc.contributor.affiliatedAuthor | 유정식 | - |
dc.contributor.affiliatedAuthor | 윤동섭 | - |
dc.citation.volume | 47 | - |
dc.citation.number | 34 | - |
dc.citation.startPage | 942 | - |
dc.citation.endPage | 944 | - |
dc.identifier.bibliographicCitation | Hepato-Gastroenterology, Vol.47(34) : 942-944, 2000 | - |
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