Cited 18 times in
Optimal lexicon of gadoxetic acid-enhanced magnetic resonance imaging for the diagnosis of hepatocellular carcinoma modified from LI-RADS
DC Field | Value | Language |
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dc.contributor.author | 박미숙 | - |
dc.contributor.author | 박영년 | - |
dc.contributor.author | 최진영 | - |
dc.contributor.author | 한경화 | - |
dc.date.accessioned | 2019-10-28T01:37:52Z | - |
dc.date.available | 2019-10-28T01:37:52Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 2366-004X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/171276 | - |
dc.description.abstract | PURPOSE: To define the optimal lexicon of major imaging findings on gadoxetic acid-enhanced MRIs to diagnose HCC to improve diagnostic performance of the LI-RADS. METHODS: Two hundred forty-one hepatic lesions (149 HCC, six other malignancies, 86 benign lesions) in 177 treatment-naïve patients at risk of HCC who underwent gadoxetic acid-MRIs from January 2013 to December 2015 were retrospectively reviewed using either histopathological or follow-up imaging findings as a standard reference. Two board-certified radiologists independently evaluated the imaging features and categorized the nodules based on the original and the following modified definitions in LI-RADS: (1) washout appearance in the portal venous phase (PVP) only versus that in the PVP or transitional phase, and (2) enhancing capsule only versus enhancing or non-enhancing capsule. Diagnostic performance and inter-observer agreement of LR-5 were assessed and compared between the algorithms using generalized estimation equation. RESULTS: The sensitivity [79.2% (95% confidence interval 71.9, 85.0)] and accuracy [84.6% (79.5, 88.7)] of LR-5 were significantly higher for modified lexicon compared with original LI-RADS [60.4% (52.3, 67.9) and 73.9% (67.9, 79.0); P < 0.001 in all cases]. There was no significant difference in specificity [93.5% (86.2, 97.0) and 95.7% (89.0, 98.4); P = 0.153]. Subgroups of lesions < or ≥ 2 cm showed similar tendencies. Inter-observer agreement for capsule appearance was fair to moderate, whereas that for other imaging findings was good to excellent. CONCLUSIONS: Compared to original LI-RADS, LI-RADS with modified lexicon showed higher sensitivity for the diagnosis of HCC using gadoxetic acid-MRI, with similar specificity. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer | - |
dc.relation.isPartOf | Abdominal Radiology | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Optimal lexicon of gadoxetic acid-enhanced magnetic resonance imaging for the diagnosis of hepatocellular carcinoma modified from LI-RADS | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Shin Hye Hwang | - |
dc.contributor.googleauthor | Sumi Park | - |
dc.contributor.googleauthor | Kyunghwa Han | - |
dc.contributor.googleauthor | Jin-young Choi | - |
dc.contributor.googleauthor | Young-Nyun Park | - |
dc.contributor.googleauthor | Mi-Suk Park | - |
dc.identifier.doi | 10.1007/s00261-019-02077-1 | - |
dc.contributor.localId | A01463 | - |
dc.contributor.localId | A01563 | - |
dc.contributor.localId | A04200 | - |
dc.relation.journalcode | J03314 | - |
dc.identifier.eissn | 2366-0058 | - |
dc.identifier.pmid | 31165907 | - |
dc.identifier.url | https://link.springer.com/article/10.1007%2Fs00261-019-02077-1 | - |
dc.subject.keyword | Diagnosis | - |
dc.subject.keyword | Gadoxetic acid | - |
dc.subject.keyword | Hepatocellular carcinoma | - |
dc.subject.keyword | MRI (Magnetic resonance imaging) | - |
dc.contributor.alternativeName | Park, Mi Sook | - |
dc.contributor.affiliatedAuthor | 박미숙 | - |
dc.contributor.affiliatedAuthor | 박영년 | - |
dc.contributor.affiliatedAuthor | 최진영 | - |
dc.citation.volume | 44 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 3078 | - |
dc.citation.endPage | 3088 | - |
dc.identifier.bibliographicCitation | Abdominal Radiology, Vol.44(9) : 3078-3088, 2019 | - |
dc.identifier.rimsid | 63848 | - |
dc.type.rims | ART | - |
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