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Clinical Characteristics and Prognostic Factors in Ankylosing Spondylitis Associated Uveitis

Authors
 Ji Hwan Lee  ;  Moonjung Choi  ;  Tyler Hyung Taek Rim  ;  Sung Chul Lee  ;  Christopher Seungkyu Lee 
Citation
 Ocular Immunology and Inflammation, Vol.27(1) : 64-69, 2019 
Journal Title
 Ocular Immunology and Inflammation 
ISSN
 0927-3948 
Issue Date
2019
Keywords
Ankylosing spondylitis ; anterior uveitis ; human leukocyte antigen B-27 ; prognosis ; uveitis
Abstract
PURPOSE: To identify the clinical features and prognostic factors of uveitis associated with ankylosing spondylitis (AS). METHODS: This retrospective, interventional case series study reviewed the medical records of 91 AS patients with uveitis. RESULTS: The characteristics of AS-associated uveitis included male preponderance (70%), average onset in the fourth decade, unilateral manifestation (87.9%), and vitreous involvement or retinal vascular leakage (36.3%). All patients had acute anterior uveitis. The best corrected visual acuity in logMAR improved from 0.8 ± 0.3 to 0.1 ± 0.2. The use of biologic agents was the only significant factor in the multivariate analysis. Patients with vitreous involvement/retinal vascular leakage were more likely to use systemic/peribulbar steroids for inflammation control, and achieved equally favorable visual outcome as in those without vitreous involvement/retinal vascular leakage. CONCLUSION: The clinical characteristics and profile of visual prognostic factors suggest an association between the severity of ocular inflammation and systemic disease.
Full Text
https://www.tandfonline.com/doi/full/10.1080/09273948.2017.1359630
DOI
10.1080/09273948.2017.1359630
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
Lee, Christopher Seungkyu(이승규) ORCID logo https://orcid.org/0000-0001-5054-9470
Lee, Ji Hwan(이지환) ORCID logo https://orcid.org/0000-0003-1759-8195
Rim, Tyler Hyungtaek(임형택)
Choi, Moonjung(최문정)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/170995
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