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응급실로 내원한 패혈성 쇼크 환자에서의 급성 신 손상 발생의 예측 인자로서 젖산/알부민 비율의 유용성
DC Field | Value | Language |
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dc.contributor.author | 고동률 | - |
dc.contributor.author | 공태영 | - |
dc.contributor.author | 김시내 | - |
dc.contributor.author | 박인철 | - |
dc.contributor.author | 유제성 | - |
dc.contributor.author | 정성필 | - |
dc.contributor.author | 좌민홍 | - |
dc.contributor.author | 황윤정 | - |
dc.date.accessioned | 2019-09-20T07:36:23Z | - |
dc.date.available | 2019-09-20T07:36:23Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1226-4334 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/170974 | - |
dc.description.abstract | Objective: The early prediction of acute kidney injury (AKI) in sepsis and the provision of prompt treatment may improve the outcomes. This study investigated the efficacy of the lactate/albumin ratio (LAR) in predicting severe AKI in cases of septic shock. Method: This retrospective, observational cohort study was performed on patients integrated prospectively in a critical pathway of early-goal-directed therapy (EGDT)/SEPSIS. Adult patients with septic shock, who were admitted to the emergency department with a normal kidney function or stage 1 disease based on the Acute Kidney Injury Network classification between January 1, 2014 and September 30, 2017, were analyzed. The outcomes were the development of sepsis-induced severe AKI within 7 days. Results: A total of 343 patients were enrolled. An increase in the LAR value at admission (odds ratio [OR], 1.85; P=0.001) was a strong independent predictor of the development of severe AKI. The increasing predictability of AKI was closely associated with a L/A ratio≥0.794 at admission (OR, 14.66; P<0.001). The area under the receiver operating characteristic curve value of the L/A ratio (0.821; 95% confidence interval [CI], 0.774-0.861; P<0.01) was higher than that of lactate (0.795; 95% CI, 0.747-0.838; P<0.01) for predicting severe AKI (P=0.032). Conclusion: L/A ratio was found to be an independent predictor of the development of severe AKI in septic shock. The prognostic performance of the L/A ratio for predicting AKI of critically ill sepsis patients was superior to that of lactate measurements. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한응급의학회 | - |
dc.relation.isPartOf | Journal of the Korean Society of Emergency Medicine (대한응급의학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 응급실로 내원한 패혈성 쇼크 환자에서의 급성 신 손상 발생의 예측 인자로서 젖산/알부민 비율의 유용성 | - |
dc.title.alternative | Lactate/albumin ratio for the prediction of the development of sepsis-induced acute kidney injury in the emergency department | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Emergency Medicine (응급의학교실) | - |
dc.contributor.googleauthor | 이정우 | - |
dc.contributor.googleauthor | 유제성 | - |
dc.contributor.googleauthor | 정성필 | - |
dc.contributor.googleauthor | 좌민홍 | - |
dc.contributor.googleauthor | 공태영 | - |
dc.contributor.googleauthor | 고동률 | - |
dc.contributor.googleauthor | 황윤정 | - |
dc.contributor.googleauthor | 이용희 | - |
dc.contributor.googleauthor | 박인철 | - |
dc.contributor.googleauthor | 김시내 | - |
dc.contributor.localId | A00113 | - |
dc.contributor.localId | A00162 | - |
dc.contributor.localId | A05313 | - |
dc.contributor.localId | A01628 | - |
dc.contributor.localId | A02507 | - |
dc.contributor.localId | A03625 | - |
dc.contributor.localId | A03947 | - |
dc.contributor.localId | A04816 | - |
dc.relation.journalcode | J01868 | - |
dc.subject.keyword | Sepsis | - |
dc.subject.keyword | Acute kidney injury | - |
dc.subject.keyword | Lactic acid | - |
dc.subject.keyword | Albumins | - |
dc.subject.keyword | Prognosis | - |
dc.contributor.alternativeName | Ko, Dong Ryul | - |
dc.contributor.affiliatedAuthor | 고동률 | - |
dc.contributor.affiliatedAuthor | 공태영 | - |
dc.contributor.affiliatedAuthor | 김시내 | - |
dc.contributor.affiliatedAuthor | 박인철 | - |
dc.contributor.affiliatedAuthor | 유제성 | - |
dc.contributor.affiliatedAuthor | 정성필 | - |
dc.contributor.affiliatedAuthor | 좌민홍 | - |
dc.contributor.affiliatedAuthor | 황윤정 | - |
dc.citation.volume | 30 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 22 | - |
dc.citation.endPage | 32 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Society of Emergency Medicine (대한응급의학회지), Vol.30(1) : 22-32, 2019 | - |
dc.identifier.rimsid | 64521 | - |
dc.type.rims | ART | - |
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