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Uterine Artery Embolization in Patients With Autoimmune Disease: A Matched Case-Control Study

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dc.contributor.author권준호-
dc.contributor.author김경민-
dc.contributor.author김만득-
dc.contributor.author송정식-
dc.contributor.author원종윤-
dc.contributor.author한기창-
dc.date.accessioned2019-09-20T07:30:31Z-
dc.date.available2019-09-20T07:30:31Z-
dc.date.issued2019-
dc.identifier.issn0361-803X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/170928-
dc.description.abstractOBJECTIVE: The purpose of this study is to investigate the safety of uterine artery embolization (UAE) for symptomatic leiomyomas in patients with autoimmune disease. MATERIALS AND METHODS: Of 1183 patients who underwent UAE for symptomatic leiomyomas, nine patients (mean age, 42.6 years; range, 34-49 years) with autoimmune disease were included in this study. An age- and disease-matched control group (n = 8) was randomly generated from our patient registry to compare the effectiveness and safety of UAE in patients with autoimmune disease. Volume reduction rates of the uterus and dominant leiomyoma and the change in C-reactive protein (CRP) levels before and after UAE were compared. RESULTS: Except for one patient who had Takayasu arteritis and indiscernible uterine arteries on angiogram, UAE was technically successful in both groups. All of the patients who underwent technically successful UAE experienced improvement or resolution of symptoms (16/16; 100%). Complete necrosis of dominant fibroids was achieved in all patients (16/16; 100%). Although there was no significant difference in the mean initial CRP level before UAE (0.4 ± 0.14 mg/L vs 1.06 ± 1.26 mg/L; p = 0.067), it was significantly higher in the autoimmune group 1 day after UAE (1.23 ± 0.6 mg/L vs 9.54 ± 6.63 mg/L; p = 0.001). There was no significant difference in the volume reduction rates of uterus and dominant leiomyoma. In the autoimmune group, there was one major adverse event that was not related to underlying disease. CONCLUSION: In patients with autoimmune disease, UAE could be considered for symptomatic leiomyomas, as long as the underlying disease is well controlled.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherSpringfield, Ill., Thomas-
dc.relation.isPartOfAmerican Journal of Roentgenology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleUterine Artery Embolization in Patients With Autoimmune Disease: A Matched Case-Control Study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorKichang Han-
dc.contributor.googleauthorMan-Deuk Kim-
dc.contributor.googleauthorWonseon Shin-
dc.contributor.googleauthorJason Jungsik Song-
dc.contributor.googleauthorJoon Ho Kwon-
dc.contributor.googleauthorGyoung Min Kim-
dc.contributor.googleauthorJong Yun Won-
dc.identifier.doi10.2214/AJR.18.20432-
dc.contributor.localIdA05085-
dc.contributor.localIdA00296-
dc.contributor.localIdA00420-
dc.contributor.localIdA02057-
dc.contributor.localIdA02443-
dc.contributor.localIdA05062-
dc.relation.journalcodeJ00116-
dc.identifier.eissn1546-3141-
dc.identifier.pmid30835520-
dc.identifier.urlhttps://www.ajronline.org/doi/full/10.2214/AJR.18.20432-
dc.subject.keywordautoimmune disease-
dc.subject.keyworddeep venous thrombosis-
dc.subject.keywordinfection-
dc.subject.keyworduterine artery embolization-
dc.contributor.alternativeNameKwon, Joon Ho-
dc.contributor.affiliatedAuthor권준호-
dc.contributor.affiliatedAuthor김경민-
dc.contributor.affiliatedAuthor김만득-
dc.contributor.affiliatedAuthor송정식-
dc.contributor.affiliatedAuthor원종윤-
dc.contributor.affiliatedAuthor한기창-
dc.citation.volume212-
dc.citation.number5-
dc.citation.startPage1148-
dc.citation.endPage1153-
dc.identifier.bibliographicCitationAmerican Journal of Roentgenology, Vol.212(5) : 1148-1153, 2019-
dc.identifier.rimsid64195-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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