50세 이상 남성에서의 흡연과 비타민 D의 상관관계: 국민건강영양조사 제5기(2011-2012년) 활용

Abstract

Background: The relationship between smoking and vitamin D status has been investigated in several studies. However, previous studies have shown conflicting results. The purpose of this study was to evaluate the association of smoking status with serum vitamin D in Korean men aged 50 years and older. Methods: Korean men aged 50 years and older who participated in the 5th Korea National Health and Nutrition Examination Survey (2011–2012, n=2,256) were included in our analysis. The subjects were categorized into current, former, and non-smoker groups based on smoking status, and the general characteristics of each group were analyzed. The current smoker group was divided into four subgroups based on the number of cigarettes smoked per day, smoking duration (years), and measured serum vitamin D levels. Results: The means of vitamin D concentrations (ng/mL) were 19.77 (standard error [SE]=0.46), 19.59 (SE=0.24), and 18.78 (SE=0.33) for non-smokers, former smokers, and current smokers, respectively. After adjustments for multiple confounders (age, education status, occupation, physical activity, body mass index, self-reported hypertension, cardiovascular disease, and respiratory disease), vitamin D concentrations decreased by 1.11 (P for trend 0.032) from non- to current smokers. Conclusion: Vitamin D concentrations were lower in current smokers than non-smokers. However, the association did not show a dose–response pattern.