399 501

Cited 17 times in

Association between depressive symptoms trajectories and cognitive function in late middle-age and older population: results of the Korean Longitudinal Study of Ageing

Authors
 Dong-Woo Choi  ;  Kyu-Tae Han  ;  Jooeun Jeon  ;  Sung-In Jang  ;  Seung Ju Kim  ;  Eun-Cheol Park 
Citation
 SCIENTIFIC REPORTS, Vol.9(1) : 7807, 2019 
Journal Title
SCIENTIFIC REPORTS
Issue Date
2019
Abstract
Thisstudyinvestigated theassociationbetweendepressive symptomsandcognitive functionaccording to four differenttrajectoriesofdepressive symptomsin thelatemiddle-agedandolderSouthKoreanpopulation. Panel data from theKoreanLongitudinal StudyofAgeingwere analyzed. We used latent classtrajectorymodels to identify fourtrajectoriesofdepressive symptoms. We performed linear mixed-effects regression analysis to assessassociationsbetweendepressive-symptomtrajectoriesand MMSE scores. Of 4,374 participants, 18.4%, 4.9%, 55.2%, and 21.5% were classified as having a low, increasing, moderate declining, and highdepressive-symptomtrajectory, respectively. Individuals with an increasingtrajectory(β = -0.729, P ≤ 0.001), moderatetrajectory(β = -0.278, P = 0.003), and hightrajectory(β = -1.605, P ≤ 0.001) had lower MMSE scores compared with those in the lowtrajectorygroup. These relationships were particularly strong among women; individuals who were physically inactive; those who were separated, divorced, or single; and those with hypertension or cerebrovascular disease. Eachtrajectorygroupfordepressive symptomswasassociatedwithcognitivedecline. Moreover, female, physically inactive, and single individuals, as well as those with hypertension and cerebrovascular disease should be particularly mindful of their mental and physical health to preventcognitivedecline.
Files in This Item:
T201901986.pdf Download
DOI
10.1038/s41598-019-44158-7
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
Yonsei Authors
Park, Eun-Cheol(박은철) ORCID logo https://orcid.org/0000-0002-2306-5398
Jang, Sung In(장성인) ORCID logo https://orcid.org/0000-0002-0760-2878
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/170251
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links