416 681

Cited 3 times in

Usefulness of the Thrombotic Microangiopathy Score as a Promising Prognostic Marker of Septic Shock for Patients in the Emergency Department

DC Field Value Language
dc.contributor.author고동률-
dc.contributor.author공태영-
dc.contributor.author김시내-
dc.contributor.author유제성-
dc.contributor.author이혜선-
dc.contributor.author정성필-
dc.contributor.author정현수-
dc.date.accessioned2019-07-11T03:35:37Z-
dc.date.available2019-07-11T03:35:37Z-
dc.date.issued2019-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/170051-
dc.description.abstractThe thrombotic microangiopathy (TMA) score based on the development and morphological characteristics of schistocytes is a rapid, simple biomarker that is easily obtained from the complete blood cell count by an automated blood cell analyzer. We aimed to determine whether the TMA score is associated with 30-day mortality of patients with early-stage septic shock. This observational cohort study was retrospectively conducted based on a prospective emergency department (ED) registry (June 2015-December 2016). We analyzed the TMA score at ED admission and 24 h later. The primary endpoint was all-cause mortality within 30 days of ED admission. A total of 221 patients were included. Increased TMA scores at time 0 (odds ratio (OR), 1.972; 95% confidence interval (CI), 1.253-3.106; p = 0.003) and at time 24 (OR, 1.863; 95% CI, 1.863-3.066; p = 0.014) were strong predictors of 30-day mortality. Increased predictability of 30-day mortality was closely associated with TMA scores ≥2 at time 0 (OR, 4.035; 95% CI, 1.651-9.863; p = 0.002) and ≥3 at time 24 (OR, 5.639; 95% CI, 2.190-14.519; p < 0.001). Increased TMA scores significantly predicted 30-day mortality for patients with severe sepsis and septic shock and can be helpful when determining the initial treatment strategies without additional costs or effort.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI AG-
dc.relation.isPartOfJOURNAL OF CLINICAL MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleUsefulness of the Thrombotic Microangiopathy Score as a Promising Prognostic Marker of Septic Shock for Patients in the Emergency Department-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Emergency Medicine (응급의학교실)-
dc.contributor.googleauthorDong Ryul Ko-
dc.contributor.googleauthorTaeyoung Kong-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorSinae Kim-
dc.contributor.googleauthorJong Wook Lee-
dc.contributor.googleauthorHyun Soo Chung-
dc.contributor.googleauthorSung Phil Chung-
dc.contributor.googleauthorJe Sung You-
dc.contributor.googleauthorJong Woo Park-
dc.identifier.doi10.3390/jcm8060808-
dc.contributor.localIdA00113-
dc.contributor.localIdA00162-
dc.contributor.localIdA05313-
dc.contributor.localIdA02507-
dc.contributor.localIdA03312-
dc.contributor.localIdA03625-
dc.contributor.localIdA03764-
dc.relation.journalcodeJ03556-
dc.identifier.eissn2077-0383-
dc.identifier.pmid31174267-
dc.subject.keywordmortality-
dc.subject.keywordpredictor-
dc.subject.keywordsepsis-
dc.subject.keywordthrombotic microangiopathy score-
dc.contributor.alternativeNameKo, Dong Ryul-
dc.contributor.affiliatedAuthor고동률-
dc.contributor.affiliatedAuthor공태영-
dc.contributor.affiliatedAuthor김시내-
dc.contributor.affiliatedAuthor유제성-
dc.contributor.affiliatedAuthor이혜선-
dc.contributor.affiliatedAuthor정성필-
dc.contributor.affiliatedAuthor정현수-
dc.citation.volume8-
dc.citation.number6-
dc.citation.startPageE808-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL MEDICINE, Vol.8(6) : E808, 2019-
dc.identifier.rimsid61853-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.