Cited 8 times in
Evaluation of Early Response to Treatment of Hepatocellular Carcinoma with Yttrium-90 Radioembolization Using Quantitative Computed Tomography Analysis
DC Field | Value | Language |
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dc.contributor.author | 김경민 | - |
dc.contributor.author | 김도영 | - |
dc.contributor.author | 김명진 | - |
dc.contributor.author | 김성원 | - |
dc.contributor.author | 안찬식 | - |
dc.contributor.author | 원종윤 | - |
dc.contributor.author | 최진영 | - |
dc.date.accessioned | 2019-07-11T03:14:32Z | - |
dc.date.available | 2019-07-11T03:14:32Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1229-6929 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/169887 | - |
dc.description.abstract | OBJECTIVE: To identify an imaging predictor for the assessment of early treatment response to yttrium-90 transarterial radioembolization (TARE) in patients with hepatocellular carcinoma (HCC), using a quantitative assessment of dynamic computed tomography (CT) images. MATERIALS AND METHODS: Dynamic contrast-enhanced CT was obtained pre- and 4 weeks post-TARE in 44 patients (34 men, 10 women; mean age, 60 years) with HCC. Computer software was developed for measuring the percentage increase in the combined delayed-enhancing area and necrotic area (pD + N) and the percentage increase in the necrotic area (pNI) in the tumor-containing segments pre- and post-TARE. Local progression-free survival (PFS) was compared between patient groups using Cox regression and Kaplan-Meier analyses. RESULTS: Post-TARE HCC with pD + N ≥ 35.5% showed significantly longer PFS than those with pD + N < 35.5% (p = 0.001). The local tumor progression hazard ratio was 17.3 (p = 0.009) for pD + N < 35.5% versus pD + N ≥ 35.5% groups. HCCs with a high pNI tended to have longer PFS, although this difference did not reach statistical significance. CONCLUSION: HCCs with a larger pD + N are less likely to develop local progression after TARE. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Society of Radiology | - |
dc.relation.isPartOf | KOREAN JOURNAL OF RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Evaluation of Early Response to Treatment of Hepatocellular Carcinoma with Yttrium-90 Radioembolization Using Quantitative Computed Tomography Analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Sungwon Kim | - |
dc.contributor.googleauthor | Do-Young Kim | - |
dc.contributor.googleauthor | Chansik An | - |
dc.contributor.googleauthor | Kyunghwa Han | - |
dc.contributor.googleauthor | Jong Yun Won | - |
dc.contributor.googleauthor | Gyoung Min Kim | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Jin-Young Choi | - |
dc.identifier.doi | 10.3348/kjr.2018.0469 | - |
dc.contributor.localId | A00296 | - |
dc.contributor.localId | A00385 | - |
dc.contributor.localId | A00426 | - |
dc.contributor.localId | A05309 | - |
dc.contributor.localId | A02268 | - |
dc.contributor.localId | A02443 | - |
dc.contributor.localId | A04200 | - |
dc.relation.journalcode | J02884 | - |
dc.identifier.eissn | 2005-8330 | - |
dc.identifier.pmid | 30799576 | - |
dc.subject.keyword | Computed tomography | - |
dc.subject.keyword | Hepatocellular carcinoma | - |
dc.subject.keyword | Quantitative analysis | - |
dc.subject.keyword | Response | - |
dc.subject.keyword | Treatment outcome | - |
dc.subject.keyword | Yttrium radioisotopes | - |
dc.contributor.alternativeName | Kim, Gyoung Min | - |
dc.contributor.affiliatedAuthor | 김경민 | - |
dc.contributor.affiliatedAuthor | 김도영 | - |
dc.contributor.affiliatedAuthor | 김명진 | - |
dc.contributor.affiliatedAuthor | 김성원 | - |
dc.contributor.affiliatedAuthor | 안찬식 | - |
dc.contributor.affiliatedAuthor | 원종윤 | - |
dc.contributor.affiliatedAuthor | 최진영 | - |
dc.citation.volume | 20 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 449 | - |
dc.citation.endPage | 458 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF RADIOLOGY, Vol.20(3) : 449-458, 2019 | - |
dc.identifier.rimsid | 62586 | - |
dc.type.rims | ART | - |
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