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Do Sleep Disorders Positively Correlate with Dry Eye Syndrome? Results of National Claim Data

Authors
 Kyu-Tae Han  ;  Ji Hyung Nam  ;  Eun-Cheol Park 
Citation
 INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, Vol.16(5) : E878, 2019 
Journal Title
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
ISSN
 1661-7827 
Issue Date
2019
Keywords
dry eye syndromes ; eye diseases ; quality of life ; sleep disorders
Abstract
Purpose: Dry eye syndrome (DES) is a common disease with an increasing occurrence. Although DES symptoms are considered mild, it can reduce quality of life for individuals. Many studies on DES have been conducted, but these focused on the use of electronic devices. Here, we investigate an association between DES and sleep disorders in the context of emerging health issues. Methods: Our data came from the National Health Insurance Service (NHIS) National Sample Cohort, which included 44,366 patients and was based on a 1:1 matching method (sleep disorder patients vs. patients without sleep disorders) during 2012⁻2015. Using survival analysis with a Cox proportional hazard model, we identified an association of sleep disorders with DES. Results: About 16.7% of all patients were diagnosed with DES, and prevalence was higher in patients with sleep disorders (sleep disorders: 19.82%, no sleep disorders: 13.67%). Survival analysis showed that sleep disorders positively correlated with DES diagnosis (Hazard Ratio (HR): 1.320, 95% Confidence Interval (CI): 1.261⁻1.382, p-value < 0.0001). Positive trends were enhanced in males, younger patients, lower economic levels, and with higher severity of comorbid. Conclusions: Our findings suggest that sleep disorder was positively associated with DES. This correlation can be helpful in effective management of both sleep disorders and DES in South Koreans.
Files in This Item:
T201901037.pdf Download
DOI
10.3390/ijerph16050878
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
Yonsei Authors
Park, Eun-Cheol(박은철) ORCID logo https://orcid.org/0000-0002-2306-5398
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/169460
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