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Long-term outcomes of laser treatment for congenital melanocytic nevi

 Yeongjoo Oh  ;  Si-Hyung Lee  ;  Jung Min Lim  ;  Kee Yang Chung  ;  Mi Ryung Roh 
 Journal of the American Academy of Dermatology, Vol.80(2) : 523-531.e12, 2019 
Journal Title
 Journal of the American Academy of Dermatology 
Issue Date
Adolescent ; Child ; Cohort Studies ; Combined Modality Therapy ; Esthetics ; Female ; Humans ; Laser Therapy/methods* ; Male ; Mohs Surgery/methods ; Nevus, Pigmented/congenital* ; Nevus, Pigmented/surgery* ; Recurrence ; Republic of Korea ; Retrospective Studies ; Risk Assessment ; Skin Neoplasms/congenital* ; Skin Neoplasms/surgery* ; Time ; Treatment Outcome ; Young Adult
congenital melanocytic nevi ; laser treatment ; partial excision ; repigmentation
BACKGROUND: Although various laser treatments have been tried for congenital melanocytic nevi (CMNs), only small retrospective studies with short-term follow-up had been done to assess outcomes. OBJECTIVE: We analyzed the long-term outcomes of laser treatment for CMN and compared these outcomes with those of a combination treatment including partial excision and lasers. METHODS: Patients with CMN treated with lasers were retrospectively reviewed, and patients with >3 years of follow-up were grouped as the long-term follow-up group. RESULTS: A total of 67 cases of CMN were reviewed. Among 20 patients (20/52, 38.5%) with near total clearance during laser-only treatment, 11 patients were in the long-term follow-up group, and 5 of 11 showed repigmentation. In total, 15 patients showed repigmentation regardless of clearance, and the mean period until repigmentation was 3.93 years from the initial treatment. Patients with partial excision and laser combination treatment showed higher Investigator's Global Assessment scores, fewer laser treatments, and shorter treatment periods compared with patients with laser-only treatment. LIMITATIONS: This is a retrospective study, and various laser devices were used. CONCLUSION: More than 4 years of follow-up is required to evaluate the efficacy of lasers in CMN, and partial excision and laser combination treatment might be an effective treatment option.
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1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Roh, Mi Ryung(노미령) ORCID logo https://orcid.org/0000-0002-6285-2490
Oh, Yeongjoo(오영주) ORCID logo https://orcid.org/0000-0003-4973-9335
Lee, Si Hyung(이시형)
Chung, Kee Yang(정기양) ORCID logo https://orcid.org/0000-0003-3257-0297
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