Cited 9 times in
Gadoxetic acid enhanced magnetic resonance imaging for prediction of the postoperative prognosis of intrahepatic mass-forming cholangiocarcinoma
DC Field | Value | Language |
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dc.contributor.author | 김명진 | - |
dc.contributor.author | 김성원 | - |
dc.contributor.author | 안찬식 | - |
dc.date.accessioned | 2019-03-15T02:26:06Z | - |
dc.date.available | 2019-03-15T02:26:06Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 2366-004X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/167476 | - |
dc.description.abstract | PURPOSE: To identify imaging markers that independently predict the post-operative outcome of intrahepatic mass-forming cholangiocarcinoma (IMCC) using gadoxetate disodium-enhanced magnetic resonance imaging (MRI). METHODS: Data from 54 patients who underwent pre-operative gadoxetate disodium-enhanced MRI and curative surgery for IMCC were retrospectively evaluated. The prognostic power of various imaging and pathological features reportedly associated with recurrence-free survival (RFS) and overall survival (OS) was analyzed using Cox regression models. A model combining imaging and pathological features was developed and its performance was evaluated using the Harrell C-index and Akaike information criterion. RESULTS: Capsule penetration (P = 0.016) and tumor size (P = 0.015) were independent markers for worse RFS, while capsule penetration (P = 0.012) and hepatic vein obstruction (HVO, P = 0.016) were independent markers for worse OS, respectively, in the imaging-based model. Capsule penetration was the only imaging marker identified in the combined prediction model of RFS, and the combined model showed a higher C-index and lower AIC value compared with the model based on pathological features alone. CONCLUSIONS: Capsule penetration and HVO on MRI are significantly worse imaging prognostic factors for post-operative outcomes in patients with IMCC. Incorporation of capsule penetration and HVO into a surgical staging system may improve prediction of the post-operative prognosis of IMCC. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer | - |
dc.relation.isPartOf | ABDOMINAL RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Gadoxetic acid enhanced magnetic resonance imaging for prediction of the postoperative prognosis of intrahepatic mass-forming cholangiocarcinoma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Sungwon Kim | - |
dc.contributor.googleauthor | Chansik An | - |
dc.contributor.googleauthor | Kyunghwa Han | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.identifier.doi | 10.1007/s00261-018-1727-5 | - |
dc.contributor.localId | A00426 | - |
dc.contributor.localId | A05309 | - |
dc.contributor.localId | A02268 | - |
dc.relation.journalcode | J03314 | - |
dc.identifier.eissn | 2366-0058 | - |
dc.identifier.pmid | 30078083 | - |
dc.identifier.url | https://link.springer.com/article/10.1007%2Fs00261-018-1727-5 | - |
dc.subject.keyword | Disodium gadoxetate | - |
dc.subject.keyword | Intrahepatic cholangiocarcinoma | - |
dc.subject.keyword | Magnetic resonance imaging | - |
dc.subject.keyword | Prognostic factors | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.affiliatedAuthor | 김명진 | - |
dc.contributor.affiliatedAuthor | 김성원 | - |
dc.contributor.affiliatedAuthor | 안찬식 | - |
dc.citation.volume | 44 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 110 | - |
dc.citation.endPage | 121 | - |
dc.identifier.bibliographicCitation | ABDOMINAL RADIOLOGY, Vol.44(1) : 110-121, 2019 | - |
dc.identifier.rimsid | 47657 | - |
dc.type.rims | ART | - |
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