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Gadoxetic acid enhanced magnetic resonance imaging for prediction of the postoperative prognosis of intrahepatic mass-forming cholangiocarcinoma

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dc.contributor.author김명진-
dc.contributor.author김성원-
dc.contributor.author안찬식-
dc.contributor.author김성원-
dc.contributor.author안찬식-
dc.date.accessioned2019-03-15T02:26:06Z-
dc.date.available2019-03-15T02:26:06Z-
dc.date.issued2019-
dc.identifier.issn2366-004X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/167476-
dc.description.abstractPURPOSE: To identify imaging markers that independently predict the post-operative outcome of intrahepatic mass-forming cholangiocarcinoma (IMCC) using gadoxetate disodium-enhanced magnetic resonance imaging (MRI). METHODS: Data from 54 patients who underwent pre-operative gadoxetate disodium-enhanced MRI and curative surgery for IMCC were retrospectively evaluated. The prognostic power of various imaging and pathological features reportedly associated with recurrence-free survival (RFS) and overall survival (OS) was analyzed using Cox regression models. A model combining imaging and pathological features was developed and its performance was evaluated using the Harrell C-index and Akaike information criterion. RESULTS: Capsule penetration (P = 0.016) and tumor size (P = 0.015) were independent markers for worse RFS, while capsule penetration (P = 0.012) and hepatic vein obstruction (HVO, P = 0.016) were independent markers for worse OS, respectively, in the imaging-based model. Capsule penetration was the only imaging marker identified in the combined prediction model of RFS, and the combined model showed a higher C-index and lower AIC value compared with the model based on pathological features alone. CONCLUSIONS: Capsule penetration and HVO on MRI are significantly worse imaging prognostic factors for post-operative outcomes in patients with IMCC. Incorporation of capsule penetration and HVO into a surgical staging system may improve prediction of the post-operative prognosis of IMCC.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherSpringer-
dc.relation.isPartOfAbdominal Radiology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleGadoxetic acid enhanced magnetic resonance imaging for prediction of the postoperative prognosis of intrahepatic mass-forming cholangiocarcinoma-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorSungwon Kim-
dc.contributor.googleauthorChansik An-
dc.contributor.googleauthorKyunghwa Han-
dc.contributor.googleauthorMyeong-Jin Kim-
dc.identifier.doi10.1007/s00261-018-1727-5-
dc.contributor.localIdA00426-
dc.contributor.localIdA05309-
dc.contributor.localIdA05309-
dc.contributor.localIdA02268-
dc.contributor.localIdA02268-
dc.contributor.localIdA05309-
dc.contributor.localIdA05309-
dc.contributor.localIdA02268-
dc.contributor.localIdA02268-
dc.relation.journalcodeJ03314-
dc.identifier.eissn2366-0058-
dc.identifier.pmid30078083-
dc.identifier.urlhttps://link.springer.com/article/10.1007%2Fs00261-018-1727-5-
dc.subject.keywordDisodium gadoxetate-
dc.subject.keywordIntrahepatic cholangiocarcinoma-
dc.subject.keywordMagnetic resonance imaging-
dc.subject.keywordPrognostic factors-
dc.contributor.alternativeNameKim, Myeong Jin-
dc.contributor.affiliatedAuthor김명진-
dc.contributor.affiliatedAuthor김성원-
dc.contributor.affiliatedAuthor김성원-
dc.contributor.affiliatedAuthor안찬식-
dc.contributor.affiliatedAuthor안찬식-
dc.contributor.affiliatedAuthor김성원-
dc.contributor.affiliatedAuthor김성원-
dc.contributor.affiliatedAuthor안찬식-
dc.contributor.affiliatedAuthor안찬식-
dc.citation.volume44-
dc.citation.number1-
dc.citation.startPage110-
dc.citation.endPage121-
dc.identifier.bibliographicCitationAbdominal Radiology, Vol.44(1) : 110-121, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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