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Improvement of Peak Cough Flow After the Application of a Mechanical In-exsufflator in Patients With Neuromuscular Disease and Pneumonia: A Pilot Study

 Ji Ho Jung  ;  Hyeon Jun Oh  ;  Jang Woo Lee  ;  Mi Ri Suh  ;  Jihyun Park  ;  Won Ah Choi  ;  Seong-Woong Kang 
 Annals of Rehabilitation Medicine, Vol.42(6) : 833-837, 2018 
Journal Title
Annals of Rehabilitation Medicine
Issue Date
Mechanical in-exsufflator ; Neuromuscular diseases ; Peak cough flow ; Pneumonia
OBJECTIVE: To investigate and demonstrate persistent increase of peak cough flow after mechanical in-exsufflator application, in patients with neuromuscular diseases and pneumonia.

METHODS: A mechanical in-exsufflator was applied with patients in an upright or semi-upright sitting position (pressure setting, +40 and -40 cmH2O; in-exsufflation times, 2-3 and 1-2 seconds, respectively). Patients underwent five cycles, with 20-30 second intervals to prevent hyperventilation. Peak cough flow without and with assistive maneuvers, was evaluated before, and 15 and 45 minutes after mechanical in-exsufflator application.

RESULTS: Peak cough flow was 92.6 L/min at baseline, and 100.4 and 100.7 L/min at 15 and 45 minutes after mechanical in-exsufflator application, respectively. Assisted peak cough flow at baseline, 15 minutes, and 45 minutes after mechanical in-exsufflator application was 170.7, 179.3, and 184.1 L/min, respectively. While peak cough flow and assisted peak cough flow increased significantly at 15 minutes after mechanical in-exsufflator application compared with baseline (p=0.030 and p=0.016), no statistical difference was observed between 15 and 45 minutes.

CONCLUSION: Increased peak cough flow after mechanical in-exsufflator application persists for at least 45 minutes.
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1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
Yonsei Authors
Kang, Seong Woong(강성웅) ORCID logo https://orcid.org/0000-0002-7279-3893
Park, Jihyun(박지현) ORCID logo https://orcid.org/0000-0002-2172-1072
Choi, Won Ah(최원아) ORCID logo https://orcid.org/0000-0003-0403-8869
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