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생체시료를 이용한 프탈레이트의 실내 노출인자 연구

Other Titles
 Study on the indoor exposure factors of phthalates using bio-monitoring data 
Authors
 양지연  ;  신동천  ;  이시은  ;  이건우  ;  김준혁  ;  이용진  ;  임영욱 
Citation
 Journal of Odor and Indoor Environment (실내환경 및 냄새 학회지), Vol.17(4) : 315-321, 2018 
Journal Title
 Journal of Odor and Indoor Environment (실내환경 및 냄새 학회지) 
ISSN
 2288-9167 
Issue Date
2018
Keywords
Edocrine disruptor ; Indoor exposure factor ; Metabolites ; Phthalate ; Risk assessment
Abstract
Phthalate is an endocrine disruptor that interferes with homeostasis and developmental regulation. It is highly toxic to the environment and is associated with various diseases of the human body. Using biological samples from 140 adult subjects, to evaluate the influencing factors which are related to contaminant concentration levels, we used correlation analysis and multiple regression analysis. Lastly, in order to analyze the health effects related to exposure to phthalates, we conducted a risk assessment by estimating acceptable daily intake exposure according to the influential factors. When we compared the concentration level according to influential factors, in general, the subjects who had engaged in home remodeling work had higher urinary phthalate metabolite concentrations levels than the subjects who had not engaged in home remodeling work. We can confirm statistically significant differences in DBP metabolites. In addition, we can confirm the concentration appeared higher in the categories such as using air freshener, sofa and foods. Through conducting a risk assessment of DEHP, BBzP, DiBP, and DnBP by using data on phthalate metabolite concentration in urine, it was found that the average concentration of all metabolites did not exceed TDI.
Files in This Item:
T201805470.pdf Download
DOI
10.15250/joie.2018.17.4.315
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Institute for Environmental Research (환경공해연구소) > 1. Journal Papers
Yonsei Authors
Shin, Dong Chun(신동천) ORCID logo https://orcid.org/0000-0003-4252-2280
Yang, Ji Yeon(양지연)
Lee, Yong Jin(이용진)
Lim, Young Wook(임영욱) ORCID logo https://orcid.org/0000-0001-8845-2850
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/167299
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