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Non-inferior low-dose coronary computed tomography angiography image quality with knowledge-based iterative model reconstruction for overweight patients

DC FieldValueLanguage
dc.contributor.author김태훈-
dc.contributor.author박철환-
dc.contributor.author오치석-
dc.contributor.author이주희-
dc.date.accessioned2019-02-12T16:41:57Z-
dc.date.available2019-02-12T16:41:57Z-
dc.date.issued2018-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/167092-
dc.description.abstractWe investigated the feasibility of low-dose coronary computed tomography angiography (CCTA), using a prospective electrocardiogram (ECG)-triggered axial scan protocol, knowledge-based iterative model reconstruction (IMR), and fixed tube current, in overweight subjects. Forty non-overweight (group A; body-mass index [BMI] < 25 kg/m2) and 40 overweight individuals (group B; BMI = 25-30 kg/m2), who underwent CCTA for coronary artery disease screening, were retrospectively and consecutively enrolled. A 64-slice CT scanner was used at 100-kVp tube voltage and 150-mA tube current, and images were reconstructed using IMR techniques. Image noise, attenuation at the aorta, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) at the proximal right and left main coronary arteries (pRCA and LMCA) were calculated. CCTA images were qualitatively evaluated using a four-point scale (1, poor; 4, excellent) and analyzed using a non-inferiority test with a pre-defined non-inferiority margin of -0.2. The mean CCTA radiation dose (Group A: 1.33 ± 0.02 mSv; Group B: 1.35 ± 0.10 mSv; p = 0.151) and mean aortic root CT attenuation values (Group A: 447.9 ± 81.6 HU; Group B: 439.5 ± 63.6 HU; p = 0.571) did not differ significantly between the two groups. The mean noise in groups A and B was 26.0 ± 4.8 HU and 29.2 ± 4.4 HU, respectively (p = 0.005). The noise reduction ratio in the groups, compared to filtered back projection, was 65.0% and 68.1%, respectively. The mean grade of image quality did not differ significantly (3.75 ± 0.04 vs. 3.71 ± 0.04, p = 0.478). Group B CCTA image quality was non-inferior (mean difference = -0.043, 95% CI = -0.162-0.077) to that of Group A. We concluded that low-dose CCTA with prospective ECG-triggering and IMR might be applied to overweight subjects, as well as to normal-weight subjects, by using a fixed tube current without an increase in tube current based on the patient's body size.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherPublic Library of Science-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleNon-inferior low-dose coronary computed tomography angiography image quality with knowledge-based iterative model reconstruction for overweight patients-
dc.title.alternative.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorIn Kyung Park-
dc.contributor.googleauthorJeffrey Park-
dc.contributor.googleauthorTae Hoon Kim-
dc.contributor.googleauthorJoohee Lee-
dc.contributor.googleauthorKyunghwa Han-
dc.contributor.googleauthorChisuk Oh-
dc.contributor.googleauthorChul Hwan Park-
dc.identifier.doi10.1371/journal.pone.0209243-
dc.contributor.localIdA01086-
dc.contributor.localIdA01722-
dc.contributor.localIdA01722-
dc.contributor.localIdA04978-
dc.contributor.localIdA04978-
dc.contributor.localIdA05545-
dc.contributor.localIdA05545-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid30586449-
dc.contributor.alternativeNameKim, Tae Hoon-
dc.contributor.affiliatedAuthor김태훈-
dc.contributor.affiliatedAuthor박철환-
dc.contributor.affiliatedAuthor박철환-
dc.contributor.affiliatedAuthor오치석-
dc.contributor.affiliatedAuthor오치석-
dc.contributor.affiliatedAuthor이주희-
dc.contributor.affiliatedAuthor이주희-
dc.citation.volume13-
dc.citation.number12-
dc.citation.startPagee209243-
dc.identifier.bibliographicCitationPLOS ONE, Vol.13(12) : e209243, 2018-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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