Breast ; Biopsy ; Ultrasound guidance ; Breast cancer diagnosis
Abstract
Purpose: The objective of our study was to determine the diagnostic accuracy, underestimation rate and false negative rate of sonographically guided core needle biopsy for breast lesions. Materials and Methods: In this retrospective study, we included 1,381 breast lesions from 1,213 patients who had undergone sonographically guided 14-gauge core needle biopsies between January 2016 and December 2016. The sonographic category of breast lesions and the pathologic results of core needle biopsies were reviewed and correlated with that of surgery or vacuum-assisted biopsy, or long term (>1yr) imaging follow-up. The positive predictive value for each sonographic category, sensitivity, underestimation rate and false negative rate of core needle biopsy were evaluated. Results: A total of 1,381 cases, the pathologic results for the core needle biopsy were benign in 636, high-risk in 208, ductal carcinoma in situ in 86, invasive cancer in 449, other malignant tumor in 2. The positive predictive values for each sonographic category were as follows: 0.0% in category 2; 0% in category 3; 1.4% in category 4a; 56.5% in category 4b; 88.7% in category 4c and 99.2% in category 5. The sensitivity of core needle biopsy was 95.9% (537/560). The underestimation rate was 10.6% (22/208) for high-risk and 34.9% (30/86) for ductal carcinoma in situ. The false negative rate was 0.2% (1/636). Conclusion: Sonographically guided core needle biopsy for 2016 year in our hospital was accurate diagnostic tool for evaluating breast lesion.