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Association Between Nonalcoholic Fatty Liver Disease and Intraocular Pressure in Korean Adults

DC FieldValueLanguage
dc.contributor.author권유진-
dc.contributor.author김지혜-
dc.contributor.author정동혁-
dc.date.accessioned2019-01-15T17:07:04Z-
dc.date.available2019-01-15T17:07:04Z-
dc.date.issued2018-
dc.identifier.issn1057-0829-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/166818-
dc.description.abstractPURPOSE: Elevated intraocular pressure (IOP) is an important modifiable risk factor predicting glaucoma progression. Recent studies have demonstrated that metabolic risk factors influence IOP. Nonalcoholic fatty liver (NAFLD) is an emerging chronic liver disease that is closely associated with metabolic syndrome, obesity, and type 2 diabetes. Therefore, we investigated the relationship between NAFLD and intraocular pressure in Korean adults. PATIENTS AND METHODS: This retrospective cross-sectional study analyzed a total of 7681 participants who visited a local health promotion center. NAFLD was defined via ultrasonography and patients were classified into 3 groups based on severity: normal, mild, and moderate to severe. We conducted multiple logistic regression analysis to examine the relationship between NAFLD and high IOP. We additionally performed multiple linear regression analysis to investigate the independent association between NAFLD and mean IOP. RESULTS: Mean IOP levels significantly and linearly increased with increasing NAFLD grades. Compared with normal, the odds ratio and 95% confidence intervals for high IOP were 1.09 (0.96-1.24) for mild NAFLD and 1.28 (1.12-1.48) for moderate to severe NAFLD after adjusting for confounding factors. NAFLD severity was noticed as an independent factor associated with mean IOP levels using stepwise and enter methods for multiple linear regression analyses. CONCLUSIONS: NAFLD severity was associated with high IOP (>15 mm Hg) in Korean adults in a dose-dependent manner.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherWolters Kluwer Health, Inc.-
dc.relation.isPartOfJOURNAL OF GLAUCOMA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleAssociation Between Nonalcoholic Fatty Liver Disease and Intraocular Pressure in Korean Adults-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Family Medicine (가정의학교실)-
dc.contributor.googleauthorKwon, Yu-Jin-
dc.contributor.googleauthorKim, Ji-Hye-
dc.contributor.googleauthorJung, Dong-Hyuk-
dc.identifier.doi10.1097/IJG.0000000000001036-
dc.contributor.localIdA04882-
dc.contributor.localIdA05620-
dc.contributor.localIdA05620-
dc.contributor.localIdA03595-
dc.contributor.localIdA03595-
dc.relation.journalcodeJ01426-
dc.identifier.eissn1536-481X-
dc.identifier.pmid30059409-
dc.identifier.urlhttps://oce.ovid.com/article/00061198-201812000-00011/HTML-
dc.contributor.alternativeNameKwon, Yu-Jin-
dc.contributor.affiliatedAuthor권유진-
dc.contributor.affiliatedAuthor김지혜-
dc.contributor.affiliatedAuthor김지혜-
dc.contributor.affiliatedAuthor정동혁-
dc.contributor.affiliatedAuthor정동혁-
dc.citation.volume27-
dc.citation.number12-
dc.citation.startPage1099-
dc.citation.endPage1104-
dc.identifier.bibliographicCitationJOURNAL OF GLAUCOMA, Vol.27(12) : 1099-1104, 2018-
dc.identifier.rimsid58194-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
7. Others (기타) > Dept. of Health Promotion (건강의학과) > 1. Journal Papers

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