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Pregnancy Rates and Outcomes of HIV-Infected Women in Korea

Authors
 Heun Choi  ;  Moo Hyun Kim  ;  Se Ju Lee  ;  Eun Jin Kim  ;  Woonji Lee  ;  Wooyong Jeong  ;  In Young Jung  ;  Jin Young Ahn  ;  Su Jin Jeong  ;  Nam Su Ku  ;  Ji Hyeon Baek  ;  Young Hwa Choi  ;  Hyo Youl Kim  ;  June Myung Kim  ;  Jun Yong Choi 
Citation
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.33(47) : e296, 2018 
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
ISSN
 1011-8934 
Issue Date
2018
Keywords
HIV ; Mother-to-Child Transmission ; Pregnancy Outcomes ; Pregnancy Rate
Abstract
Background: Antepartum, intrapartum, and postpartum preventive measures with antiretroviral drugs, appropriate delivery methods, and discouraging breastfeeding significantly decrease the risk of mother-to-child transmission of human immunodeficiency virus (HIV) infection. Herein, we investigated the pregnancy outcomes in HIV-infected Korean women.

Methods: We retrospectively reviewed medical records of childbearing-age HIV-infected women between January 2005 and June 2017 at four tertiary care hospitals in Korea.

Results: Among a total of 95 HIV infected women of child-bearing age with 587.61 years of follow-up duration, 15 HIV-infected women experienced 21 pregnancies and delivered 16 infants. The pregnancy rate was 3.57 per 100 patient-years. Among the 21 pregnancies, five ended with an induced abortion, and 16 with childbirth including two preterm deliveries at 24 and 35 weeks of gestation, respectively. The two preterm infants had low birth weight and one of them died 10 days after delivery due to respiratory failure. Among the 14 full-term infants, one infant was small for gestational age. There were no HIV-infected infants.

Conclusion: The pregnancy rate of HIV-infected women in Korea is lower than that of the general population. Although several adverse pregnancy outcomes were observed, mother-to-child transmission of HIV infection was successfully prevented with effective preventive measures.
Files in This Item:
T201805407.pdf Download
DOI
10.3346/jkms.2018.33.e296
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Ku, Nam Su(구남수) ORCID logo https://orcid.org/0000-0002-9717-4327
Kim, June Myung(김준명)
Ahn, Jin Young(안진영) ORCID logo https://orcid.org/0000-0002-3740-2826
Jeong, Su Jin(정수진) ORCID logo https://orcid.org/0000-0003-4025-4542
Jung, In Young(정인영)
Choi, Jun Yong(최준용) ORCID logo https://orcid.org/0000-0002-2775-3315
Choi, Heun(최흔) ORCID logo https://orcid.org/0000-0002-9622-9381
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/166567
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