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Detection of recurrent hepatocellular carcinoma on post-operative surveillance: comparison of MDCT and gadoxetic acid-enhanced MRI
DC Field | Value | Language |
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dc.contributor.author | 정용은 | - |
dc.contributor.author | 김명진 | - |
dc.contributor.author | 김기황 | - |
dc.contributor.author | 박미숙 | - |
dc.contributor.author | 임준석 | - |
dc.contributor.author | 최진영 | - |
dc.date.accessioned | 2018-12-06T16:40:00Z | - |
dc.date.available | 2018-12-06T16:40:00Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0942-8925 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/166041 | - |
dc.description.abstract | OBJECTIVE: To compare the accuracy of multidetector computed tomography (MDCT) and gadoxetic acid-enhanced magnetic resonance imaging (MRI) for the detection of intrahepatic tumor recurrence after curative resection of hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Fifty-six patients who underwent MDCT and gadoxetic acid-enhanced MRI for postoperative surveillance after resection of HCC were retrospectively analyzed; 26 patients had a recurrence (36 lesions) and 30 patients did not. Recurrent HCCs were confirmed by histological examinations in two, typical dynamic imaging findings on CT and/or MRI in 28, and by demonstration of growth or tumor staining on angiography on six. Two reviewers graded the confidence for the presence of recurrence on CT and MRI, using a five-point scale. The jackknife free-response receiver operating characteristic method was used to compare diagnostic performance. The accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated. RESULTS: For 36 recurrent lesions, the figure of merit was significantly higher for MRI than MDCT for detecting recurrence for both reviewers (p < 0.005 for both reviewers). In lesion-by-lesion analysis, the sensitivity was significantly higher on MRI (100% for reviewer 1 and 97% for reviewer 2) than on MDCT (44.4% and 66.6%) for both reviewers (p < 0.005 for both reviewers). Also in patient-by-patient analysis, sensitivity was significantly higher on MRI (100% and 96.1%) than on MDCT (57.6% and 76.9%) for both reviewers (p < 0.05 for both reviewers). CONCLUSION: Gadoxetic acid-enhanced MRI is superior to MDCT for detecting intrahepatic recurrence after curative resection of HCC. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer International | - |
dc.relation.isPartOf | ABDOMINAL IMAGING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Detection of recurrent hepatocellular carcinoma on post-operative surveillance: comparison of MDCT and gadoxetic acid-enhanced MRI | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Kyung Ah Kim | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Jin-Young Choi | - |
dc.contributor.googleauthor | Mi-Suk Park | - |
dc.contributor.googleauthor | Joon Seok Lim | - |
dc.contributor.googleauthor | Yong Eun Chung | - |
dc.contributor.googleauthor | Ki Whang Kim | - |
dc.identifier.doi | 10.1007/s00261-013-0064-y | - |
dc.contributor.localId | A03662 | - |
dc.contributor.localId | A00426 | - |
dc.relation.journalcode | J00002 | - |
dc.identifier.eissn | 1432-0509 | - |
dc.identifier.pmid | 24384804 | - |
dc.identifier.url | https://link.springer.com/article/10.1007%2Fs00261-013-0064-y | - |
dc.contributor.alternativeName | Chung, Yong Eun | - |
dc.contributor.affiliatedAuthor | 정용은 | - |
dc.contributor.affiliatedAuthor | 김명진 | - |
dc.citation.volume | 39 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 291 | - |
dc.citation.endPage | 299 | - |
dc.identifier.bibliographicCitation | ABDOMINAL IMAGING, Vol.39(2) : 291-299, 2014 | - |
dc.identifier.rimsid | 59270 | - |
dc.type.rims | ART | - |
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