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Cited 3 times in

Visceral fat thickness and its associations with pubertal and metabolic parameters among girls with precocious puberty.

DC Field Value Language
dc.contributor.author권아름-
dc.contributor.author김호성-
dc.contributor.author서정환-
dc.contributor.author윤춘식-
dc.contributor.author채현욱-
dc.date.accessioned2018-11-16T16:55:02Z-
dc.date.available2018-11-16T16:55:02Z-
dc.date.issued2018-
dc.identifier.issn2287-1012-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/165469-
dc.description.abstractPURPOSE: This study aimed to investigate associations of central obesity with sexual maturation and metabolic parameters in Korean girls with precocious puberty. METHODS: This retrospective study evaluated data from 72 girls under 8 years of age with a chief complaint of early breast development. The patients were categorized as central precocious puberty (CPP) subjects or non-CPP subjects based on their gonadotropin-releasing hormone stimulation test results. Visceral fat thickness (VFT) was measured using ultrasonography and defined as the distance from the linea alba to the aorta. Patient anthropometric, metabolic, and hormonal parameters were also evaluated. RESULTS: Increased VFT was correlated with an earlier onset of thelarche among all study subjects (r=-0.307, P=0.034). Overweight CPP subjects showed higher insulin resistance than normal weight CPP subjects. Insulin resistance was not significantly different between overweight and normal weight non-CPP subjects. VFT was not significantly different between CPP and non-CPP subjects (2.22±0.79 cm vs. 2.74±1.47 cm, P=0.169). However, overweight and obese CPP subjects (body mass index percentile>85%) had lower VFT than non-CPP obese subjects. CONCLUSION: Central obesity, defined using ultrasonography-measured VFT, might be associated with early pubertal development in Korean girls. However, VFT was not higher in CPP than non-CPP patients and was not significantly correlated with insulin resistance. Further longitudinal studies with a larger cohort are needed.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherKorean Society of Pediatric Endocrinology-
dc.relation.isPartOfANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleVisceral fat thickness and its associations with pubertal and metabolic parameters among girls with precocious puberty.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아청소년과학교실)-
dc.contributor.googleauthorDong Wook Kim-
dc.contributor.googleauthorJunghwan Suh-
dc.contributor.googleauthorAh Reum Kwon-
dc.contributor.googleauthorHyun Wook Chae-
dc.contributor.googleauthorChoon Sik Yoon-
dc.contributor.googleauthorHo-Seong Kim-
dc.contributor.googleauthorDuk Hee Kim-
dc.identifier.doi10.6065/apem.2018.23.2.81-
dc.contributor.localIdA00228-
dc.contributor.localIdA01184-
dc.contributor.localIdA05629-
dc.contributor.localIdA02615-
dc.contributor.localIdA04026-
dc.relation.journalcodeJ00175-
dc.identifier.eissn2287-1292-
dc.identifier.pmid29969879-
dc.subject.keywordPrecocious puberty-
dc.subject.keywordUltrasound-
dc.subject.keywordVisceral fat thickness-
dc.contributor.alternativeNameKwon, Ah Reum-
dc.contributor.alternativeNameKim, Ho Seong-
dc.contributor.alternativeNameSuh, Junghwan-
dc.contributor.alternativeNameYoon, Choon Sik-
dc.contributor.alternativeNameChae, Hyun Wook-
dc.contributor.affiliatedAuthor권아름-
dc.contributor.affiliatedAuthor김호성-
dc.contributor.affiliatedAuthor서정환-
dc.contributor.affiliatedAuthor윤춘식-
dc.contributor.affiliatedAuthor채현욱-
dc.citation.volume23-
dc.citation.number2-
dc.citation.startPage81-
dc.citation.endPage87-
dc.identifier.bibliographicCitationANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, Vol.23(2) : 81-87, 2018-
dc.identifier.rimsid58933-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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