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Risk factors for osteoporosis in chronic inflammatory demyelinating polyradiculoneuropathy.

Authors
 Seung Woo Kim  ;  Young‐Chul Choi  ;  Seung Min Kim  ;  Ha Young Shin 
Citation
 MUSCLE & NERVE, Vol.58(3) : 407-412, 2018 
Journal Title
 MUSCLE & NERVE 
ISSN
 0148-639X 
Issue Date
2018
Keywords
bone mineral density ; chronic inflammatory demyelinating polyradiculoneuropathy ; corticosteroid ; inflammatory neuropathy ; osteoporosis
Abstract
INTRODUCTION: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) patients possess multiple risk factors for osteoporosis, but few studies have evaluated bone mineral density (BMD) in CIDP patients. METHODS: We retrospectively compared the BMD of CIDP patients with that of normal controls, and evaluated the clinical factors associated with osteoporosis. RESULTS: Total BMD was lower in CIDP patients than in normal controls (P = 0.017). In a comparison of 16 osteoporotic CIDP patients with 25 non-osteoporotic patients, the cumulative prednisolone dose was lower (P = 0.022) and the duration from disease onset to BMD measurement was shorter (P = 0.014) in osteoporotic patients than in non-osteoporotic patients. Function, as measured by modified Rankin scale score within 3 years of the BMD measurement, was worse in osteoporotic than in non-osteoporotic patients (P = 0.008). DISCUSSION: BMD in CIDP patients was significantly lower than in normal controls. Functional status rather than cumulative steroid dose was associated with osteoporosis. Muscle Nerve 58: 407-412, 2018.
Full Text
https://onlinelibrary.wiley.com/doi/full/10.1002/mus.26175
DOI
10.1002/mus.26175
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seung Min(김승민) ORCID logo https://orcid.org/0000-0002-4384-9640
Kim, Seung Woo(김승우) ORCID logo https://orcid.org/0000-0002-5621-0811
Shin, Ha Young(신하영) ORCID logo https://orcid.org/0000-0002-4408-8265
Choi, Young Chul(최영철) ORCID logo https://orcid.org/0000-0001-5525-6861
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/165311
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