0 180

Cited 0 times in

Step-down strategy in antiviral resistant chronic hepatitis B patients who achieved viral suppression with rescue combination therapy

Authors
 Dong Yun Kim  ;  Jun Yong Park 
Citation
 FUTURE VIROLOGY, Vol.13(10) : 711-717, 2018 
Journal Title
 FUTURE VIROLOGY 
ISSN
 1746-0794 
Issue Date
2018
Keywords
chronic hepatitis B ; combination therapy ; drug resistance ; hepatitis B virus ; step-down therapy
Abstract
In the treatment of chronic hepatitis B (CHB) patients with drug resistance, rescue combination therapy leads to viral suppression in almost all patients. However, once it is achieved, lifelong maintenance especially, by using combination therapy is not always possible in a significant proportion of patients. At present, there is no consensus on whether it is possible to switch to monotherapy from combination therapy. However, there is robust evidence to support step-down therapy, which involves switching from combination therapy to monotherapy in antiviral resistant CHB patients who achieve complete viral response from combination therapy. We review the evidence in favor of switching to monotherapy in antiviral resistant CHB patients who achieve complete viral response by combination therapy.
Full Text
https://www.futuremedicine.com/doi/10.2217/fvl-2018-0078
DOI
10.2217/fvl-2018-0078
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Jun Yong(박준용) ORCID logo https://orcid.org/0000-0001-6324-2224
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/165232
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links