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Step-down strategy in antiviral resistant chronic hepatitis B patients who achieved viral suppression with rescue combination therapy
DC Field | Value | Language |
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dc.contributor.author | 박준용 | - |
dc.date.accessioned | 2018-11-16T16:41:48Z | - |
dc.date.available | 2018-11-16T16:41:48Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1746-0794 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/165232 | - |
dc.description.abstract | In the treatment of chronic hepatitis B (CHB) patients with drug resistance, rescue combination therapy leads to viral suppression in almost all patients. However, once it is achieved, lifelong maintenance especially, by using combination therapy is not always possible in a significant proportion of patients. At present, there is no consensus on whether it is possible to switch to monotherapy from combination therapy. However, there is robust evidence to support step-down therapy, which involves switching from combination therapy to monotherapy in antiviral resistant CHB patients who achieve complete viral response from combination therapy. We review the evidence in favor of switching to monotherapy in antiviral resistant CHB patients who achieve complete viral response by combination therapy. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Future Medicine Ltd. | - |
dc.relation.isPartOf | FUTURE VIROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Step-down strategy in antiviral resistant chronic hepatitis B patients who achieved viral suppression with rescue combination therapy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Dong Yun Kim | - |
dc.contributor.googleauthor | Jun Yong Park | - |
dc.identifier.doi | 10.2217/fvl-2018-0078 | - |
dc.contributor.localId | A01675 | - |
dc.relation.journalcode | J03513 | - |
dc.identifier.eissn | 1746-0808 | - |
dc.identifier.url | https://www.futuremedicine.com/doi/10.2217/fvl-2018-0078 | - |
dc.subject.keyword | chronic hepatitis B | - |
dc.subject.keyword | combination therapy | - |
dc.subject.keyword | drug resistance | - |
dc.subject.keyword | hepatitis B virus | - |
dc.subject.keyword | step-down therapy | - |
dc.contributor.alternativeName | Park, Jun Yong | - |
dc.contributor.affiliatedAuthor | 박준용 | - |
dc.citation.volume | 13 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 711 | - |
dc.citation.endPage | 717 | - |
dc.identifier.bibliographicCitation | FUTURE VIROLOGY, Vol.13(10) : 711-717, 2018 | - |
dc.identifier.rimsid | 58649 | - |
dc.type.rims | ART | - |
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