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Recent strategies to design vascular theranostic nanoparticles

Authors
 Mukesh K. Gupta  ;  Yunki Lee  ;  Timothy C. Boire  ;  Jung-Bok Lee  ;  Won Shik Kim  ;  Hak-Joon Sung 
Citation
 Nanotheranostics, Vol.1(2) : 166-177, 2017 
Journal Title
 Nanotheranostics 
Issue Date
2017
Keywords
nanotheranostics ; vascular diseases
Abstract
Vascular disease is a leading cause of death and disability worldwide. Current surgical intervention and treatment options for vascular diseases have exhibited limited long-term success, emphasizing the need to develop advanced treatment paradigms for early detection and more effective treatment of dysfunctional cells in a specific blood vessel lesion. Advances in targeted nanoparticles mediating cargo delivery enables more robust prevention, screening, diagnosis, and treatment of vascular disorders. In particular, nanotheranostics integrates diagnostic imaging and therapeutic function into a single agent, and is an emerging platform towards more effective and localized vascular treatment. This review article highlights recent advances and current challenges associated with the utilization of targeted nanoparticles for real-time diagnosis and treatment of vascular diseases. Given recent developments, nanotheranostics offers great potential to serve as an effective platform for targeted, localized, and personalized vascular treatment.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/165065
Files in This Item:
T999900137.pdf Download
DOI
10.7150/ntno.18531
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실)
Yonsei Authors
성학준(Sung, Hak-Joon) ORCID logo https://orcid.org/0000-0003-2312-2484
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