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Changes in biomechanically corrected intraocular pressure and dynamic corneal response parameters before and after transepithelial photorefractive keratectomy and femtosecond laser-assisted laser in situ keratomileusis

Authors
 Hun Lee  ;  Cynthia J. Roberts  ;  Tae-im Kim  ;  Renato Ambrósio Jr.  ;  Ahmed Elsheikh  ;  David Sung Yong Kang 
Citation
 JOURNAL OF CATARACT AND REFRACTIVE SURGERY, Vol.43(12) : 1495-1503, 2017 
Journal Title
 JOURNAL OF CATARACT AND REFRACTIVE SURGERY 
ISSN
 0886-3350 
Issue Date
2017
Abstract
PURPOSE: To evaluate the changes in biomechanically corrected intraocular pressure (IOP) and new dynamic corneal response parameters measured by a dynamic Scheimpflug analyzer before and after transepithelial photorefractive keratectomy (PRK) and femtosecond laser-assisted laser in situ keratomileusis (LASIK). SETTING: Yonsei University College of Medicine and Eyereum Eye Clinic, Seoul, South Korea. DESIGN: Retrospective case series. METHODS: Medical records of patients having transepithelial PRK or femtosecond-assisted LASIK were examined. The primary outcome variables were biomechanically corrected IOP and dynamic corneal response parameters, including deformation amplitude ratio 2.0 mm, stiffness parameter at first applanation, Ambrósio relational thickness through the horizontal meridian, and integrated inverse radius before the procedure and 6 months postoperatively. RESULTS: Of the 129 patients (129 eyes) in the study, 65 had transepithelial PRK and 64 had femtosecond-assisted LASIK. No significant differences in biomechanically corrected IOP were noted before and after surgery. The deformation amplitude ratio 2.0 mm and integrated inverse radius increased, whereas the stiffness parameter at first applanation and the Ambrósio relational thickness through the horizontal meridian decreased after surgery (P < .001). The changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P < .001). Using analysis of covariance, with refractive error change or corneal thickness change as a covariate, the changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P < .001). CONCLUSIONS: The dynamic Scheimpflug analyzer showed stable biomechanically corrected IOP measurement before and after surgery. The changes in dynamic corneal response parameters were smaller with transepithelial PRK than with femtosecond-assisted LASIK, indicating less of a biomechanical effect with transepithelial PRK.
Full Text
https://www.sciencedirect.com/science/article/pii/S0886335017307332
DOI
10.1016/j.jcrs.2017.08.019
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Sung Yong(강성용)
Kim, Tae Im(김태임) ORCID logo https://orcid.org/0000-0001-6414-3842
Lee, Hun(이훈)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/165041
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