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SLA 처리 티타늄 표면에서의 유전자발현에 대한 상온대기압 플라즈마의 효과

Other Titles
 Effects of non-thermal atmospheric pressure air plasma on gene expression at SLA- treated titanium surfaces 
Authors
 서혜연  ;  강민경  ;  최유리  ;  권재성  ;  최은하  ;  김경남 
Citation
 Korean Journal of Dental Materials (대한치과재료학회지), Vol.42(1) : 15-20, 2015 
Journal Title
 Korean Journal of Dental Materials (대한치과재료학회지) 
ISSN
 2384-4434 
Issue Date
2015
Keywords
atmospheric pressure plasma ; SLA-treated surface ; osseointegration
Abstract
Dental implants manufacturers have developed high hydrophilic and rough implant surfaces which in turn exhibited better osseointegration than conventional ones. Based on in vitro studies, sand blast, large grit, acid etching(SLA)-treated surfaces with microstructural characteristics may promote the process of osseointegration. But when the SLA surface is kept dry in the air, it becomes hydrophobic. Appropriate non-thermal atmospheric pressure air plasma jet(air-NTAPPJ) processes render surfaces hydrophilic. The purpose of this research is to air-NTAPPJ on SLA surface treatment to improve the osteogenic functionality. The experiment was carried out through the a cytotoxicity assay and real-time reverse transcriptase-polymerase chain reaction(RT-PCR). The results were that the cell viability and gene expression of ALP, OCN, OPN, and Runx-2 of rMSC enhanced by air-NTAPPJ treated. Thus, air-NTAPPJ application can lead to an improved osseointegration.
Files in This Item:
T999900123.pdf Download
DOI
10.14815/kjdm.2015.42.1.15
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Jae-Sung(권재성) ORCID logo https://orcid.org/0000-0001-9803-7730
Kim, Kyoung Nam(김경남)
Choi, Yu Ri(최유리)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/165032
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