Cited 11 times in
β-Catenin activated hepatocellular adenoma: a report of three cases in Korea
DC Field | Value | Language |
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dc.contributor.author | 이형진 | - |
dc.date.accessioned | 2018-10-29T16:40:12Z | - |
dc.date.available | 2018-10-29T16:40:12Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/163846 | - |
dc.description.abstract | Hepatocellular adenoma (HCA) is an uncommon benign hepatic tumor, and the use of oral contraceptives is known to contribute to the development of HCA. Recently, a genotype and phenotype classification system for HCA was suggested, and malignant transformation to hepatocellular carcinoma (HCC) was shown to be strongly associated with activating mutations in β-catenin. Here, we report three cases of HCA in Korean patients: 7-cm, inflammatory and β-catenin-activated HCA with HCC transformation in a 46-year-old man; 13-cm, β-catenin-activated HCA with cytological atypia in a 23-year-old woman; and 10-cm, pigmented, inflammatory and β-catenin-activated HCA in a 36-year-old man. All cases exhibited the nuclear expression of β-catenin and diffuse cytoplasmic expression of glutamine synthetase upon immunohistochemical staining. All tumors were completely resected, and the patients were followed for 3 to 6 years with no evidence of local recurrence or metastasis. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Editorial Office of Gut and Liver | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Carcinoma, Hepatocellular/metabolism* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver Neoplasms/metabolism* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Young Adult | - |
dc.subject.MESH | beta Catenin/metabolism* | - |
dc.title | β-Catenin activated hepatocellular adenoma: a report of three cases in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.googleauthor | Gi Jeong Kim | - |
dc.contributor.googleauthor | Jae Yeon Seok | - |
dc.contributor.googleauthor | Hyungjin Rhee | - |
dc.contributor.googleauthor | Jin-Young Choi | - |
dc.contributor.googleauthor | Jin-Sub Choi | - |
dc.contributor.googleauthor | Kyung Sik Kim | - |
dc.contributor.googleauthor | Swan Thung | - |
dc.contributor.googleauthor | Young Nyun Park | - |
dc.identifier.doi | 10.5009/gnl.2014.8.4.452 | - |
dc.contributor.localId | A05171 | - |
dc.relation.journalcode | J00954 | - |
dc.identifier.eissn | 2005-1212 | - |
dc.identifier.pmid | 25071913 | - |
dc.subject.keyword | Adenoma | - |
dc.subject.keyword | Beta catenin | - |
dc.subject.keyword | Carcinoma | - |
dc.subject.keyword | Glutamine synthetase | - |
dc.subject.keyword | hepatocellular | - |
dc.subject.keyword | liver cell | - |
dc.contributor.alternativeName | Rhee, Hyungjin | - |
dc.contributor.affiliatedAuthor | 이형진 | - |
dc.citation.volume | 8 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 452 | - |
dc.citation.endPage | 458 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, Vol.8(4) : 452-458, 2014 | - |
dc.identifier.rimsid | 60623 | - |
dc.type.rims | ART | - |
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