0 62

Cited 0 times in

Characteristics of Autonomic Activity and Reactivity During Rest and Emotional Processing and Their Clinical Correlations in Somatic Symptom Disorder

Authors
 Deokjong Lee  ;  Se Joo Kim  ;  Jooah Cheon  ;  Eun Hee Hwang  ;  Young-chul Jung  ;  Jee In Kang 
Citation
 Psychosomatic Medicine, Vol.80(8) : 690-697, 2018 
Journal Title
 Psychosomatic Medicine 
ISSN
 0033-3174 
Issue Date
2018
Keywords
autonomic nervous system ; heart rate variability ; somatic symptom disorder
Abstract
OBJECTIVE: Altered autonomic nervous system activity is considered to be involved in the pathophysiology of somatic symptom disorder (SSD). This study aimed to investigate whether patients with SSD have disturbed autonomic activity during rest and reactivity to emotional processing and whether altered autonomic nervous system correlates with clinical characteristics and interoceptive accuracy in SSD. METHODS: We recruited 23 patients with SSD and 20 healthy controls. Heart rate variability (HRV) was assessed during recording at rest and during performance of an emotional face dot-probe task. Alpha-amylase responses were also assessed. Patients with SSD completed a self-assessment survey and heart beat perception task, which reflects interoceptive awareness. RESULTS: Patients with SSD had lower low-frequency HRV, high-frequency HRV, standard deviation of normal to normal R-R intervals (SDNN), and proportion of successive R-R intervals greater than 50 milliseconds (pNN50) at rest (p < .05). The reactivity scores (during-task activity minus resting activity) for SDNN and pNN50 were significantly different between patients with SSD and controls (SDNN: p = .013; pNN50: p = .008). In addition, resting HRV parameters (low-frequency, high-frequency, SDNN, pNN50) correlated with heart beat perception error (p < .01) in patients with SSD. No significant differences in α-amylase activity were found. CONCLUSIONS: Our findings showed that patients with SSD have altered resting-state autonomic activity and reactivity to emotional processing, and the resting-state autonomic activity correlated with their interoceptive awareness. These findings suggest that disturbed interactions between the autonomic nervous, affective, and interoceptive systems may be involved in the pathophysiology of SSD
Full Text
https://insights.ovid.com/pubmed?pmid=29995000
DOI
10.1097/PSY.0000000000000622
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Jee In(강지인) ORCID logo https://orcid.org/0000-0002-2818-7183
Kim, Se Joo(김세주) ORCID logo https://orcid.org/0000-0002-5438-8210
Jung, Young Chul(정영철) ORCID logo https://orcid.org/0000-0002-0578-2510
Cheon, Joo Ah(천주아)
Export
RIS (EndNote)
XLS (Excel)
XML
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/163720
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse