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Other Titles
 Stem cells: general information and perspectives 
Authors
 허용준  ;  김동욱 
Citation
 Journal of the Korean Neurological Association, Vol.54(5) : 450-453, 2011 
Journal Title
 Journal of the Korean Neurological Association 
ISSN
 1738-1428 
Issue Date
2011
Keywords
Stem cells ; Embryonic stem cells ; Adult stem cells ; Induced pluripotent stem cells ; Regenerative medicine
Abstract
We are now in the middle of stem cell war. Each country is trying to invest a large amount of funds into stem cell research. This is due to a potentiality of stem cells. Stem cells are capable of proliferating in an undifferentiated manner and are able to differentiate into a desired cell lineage under certain conditions. These abilities make stem cells an appealing source for cell replacement therapies (regenerative medicine), the study of developmental biology and drug/toxin screening. In addition to embryonic and adult stem cells, induced pluripotent stem (iPS) cells has been recently generated through reprogramming from adult tissue cells such as fibroblasts. This technique has opened up new avenues to generate patient- and disease-specific pluripotent stem cells. Human iPS cells may be useful for gaining valuable insight into the pathophysiology of disease, as well as for discovering for new prognostic biomarkers and drug screening. Moreover, the iPS cell technology may play a major role in immune-matched clinical application in the future. In this chapter, we introduce general characteristics of various stem cells, clinical application of stem cells and future perspectives
Files in This Item:
T999900020.pdf Download
DOI
10.5124/jkma.2011.54.5.450
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Physiology (생리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
Yonsei Authors
Kim, Dong Wook(김동욱) ORCID logo https://orcid.org/0000-0002-5025-1532
Huh, Yong Jun(허용준)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/163566
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