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온혈구검사와 일반화학검사의 기능의학적 재해석

Other Titles
 Interpretations of complete blood count and clinical chemistry from functional medicine perspectives 
Authors
 Yong-Jae Lee 
Citation
 Journal of Korean Institute for Functional Medicine, Vol.1 : 19-25, 2018 
Journal Title
 Journal of Korean Institute for Functional Medicine 
Issue Date
2018
Keywords
Complete blood count ; Clinical chemistry ; Inflammation ; Frailty
Abstract
Accumulating evidence suggests that cancer, cardiovascular disease, atherosclerosis, type 2 diabetes, metabolic syndrome, sarcopenia, and autonomic dysfunction could be predicted by using leukocyte count and clinical chemistry tests in addition to the traditional interpretations. This review focused on the integrative interpretations of complete blood count (CBC) and clinical chemistry from functional medicine perspectives. We conducted a review to assess the epidemiological associations between CBC and clinical chemistry from the database of PubMed, EMBASE, Cochrane. The CBC tests such as leukocyte count and platelet count and clinical chemistry tests including serum blood glucose, lipid profiles, liver enzymes, uric acid, and bilirubin are widely performed in primary care setting. Cancer, cardiovascular disease, and cerebrovascular disease are the three major causes of death in developed countries, wherein the crucial pathophysiology involves oxidative stress and chronic low-grade inflammation. Low-grade inflammation accumulates due to the combination of innate constitution, detoxification, intestinal health, resilience to cope with stress, lifestyle behaviors including smoking, drinking and sleep, which in turn leads to higher inflammatory markers in blood. On the other hand, individuals with weakness also express various symptoms. Frailty is a common complication in patients with multiple discomforts such as sarcopenia, chronic fatigue, headache, dizziness, poor circulation, and multiple pain. Thus, it is important to understand who is in inflammation or in a weak state from a functional medicine perspective. CBC or clinical chemistry may help to identify individuals who are not functionally optimally are often in chronic inflammation or frailty state.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/163480
DOI
10.32581/jkifm.2018.1.19
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실)
Yonsei Authors
이용제(Lee, Yong Jae) ORCID logo https://orcid.org/0000-0002-6697-476X
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